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Ulrike BINDER Tel.: +43 (0)512 9003-70748 |
Biographical sketch and research interests
Studies of Microbiology and Molecular Biology at the Leopold-Franzens-University, Innsbruck, Austria – Master and PhD in Microbiology; Internships at Technical University Denmark, University of Edinburgh, National Institute of Chemistry, Ljubljana, University of Murcia, Spain - Habilitation at the Medical University of Innsbruck for Microbiology
human fungal pathogens, Mucormycetes, Aspergillus spp., Candida spp., antifungal susceptibility and resistance, novel antifungal agents, mechanisms of resistance, alternative in vitro and in vivo models, Galleria mellonella, host-pathogen interactions, viruelnce traits, bioluminescent reporter strains, bioluminescent imaging
Current Position
Senior Scientist (permanent position)
Education
| 2019 | Venia docendi/Habilitation for the subject Microbiology "Alternative models to study antifungal susceptibility and virulence of pathogenic molds" |
| 2017 | Completion of the "Helene Wastl Medizin Mentoring programme" of the MUI |
| 2012 | Diploma "CBS course on Medical Mycology" |
| 2005 - 2009 |
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| 2003 - 2005 |
Master thesis at the Biocenter, Division of Molecular Biology, Medical University Innsbruck. "Characterisation of antifungal proteins secreted by aspergilli", passed with distinction |
| 1999 - 2005 | Studies of Biology/Microbiology at the Leopold-Franzens-University Innsbruck, Austria |
Career History
| Since 2020 | Senior Scientist (permanent position) at the Institute of Hygiene and Medical Microbiology; group leader within the Mycology Unit of the Institute |
| 2021 | Research visit to the Department of Fungal Genetics, University of Murcia, Spain, collaboration with Prof. Victoriano Garre, “Genetic modification in Rhizopus microsporus”; Talento programme |
| 2019 | Venida docendi/Habilitation for the subject Microbiology “Alternative models to study antifungal susceptibility and virulence of pathogenic molds” |
| 2015-2019 | Senior Scientist/Postdoc (50%/50%) at the Institute of Hygiene and Medical Microbiology; group leader within the Mycology Unit of the Institute |
| 2017 | Visiting researcher at the Department of Fungal Genetics, University of Murcia, Spain, collaboration with Prof. Victoriano Garre, “Genetic modification in Mucor circinelloides”; EMBO fellowship |
| 2015 | Research visit at the Institute of Microbiology, CHUV Lausanne; Assoc.Prof. Dr. D. Sanglard. Training in molecular biological techniques to be applied in the Galleria mellonella model |
| 2012 | Research visit at the National University of Ireland Maynooth, Department of Biology, collaboration with Dr. Kevin Kavanagh; "Suitability and adaptation of the alternative in vivo model Galleria mellonella for A. terreus and Mucorales" |
| 2011-2015 | Postdoctoral research fellow/group leader at the Institute of Hygiene and Medical Microbiology |
| 2009-2010 | Postdoctoral research fellow at the Division of Molecular Biology, Biocenter, Innsbruck Medical University |
| 2008/2009 | Visiting researcher at the Institute of Cell Biology, University of Edinburgh, collaboration with Prof. Dr. ND Read. “The antifungal protein PAF disrupts calcium signalling in N. crassa”, EMBO fellowship |
| 2007 | Visiting researcher at the Institute of Cell Biology, University of Edinburgh. Collaboration with Prof. Dr. ND Read “The influence of antifungal proteins on the calcium signal transduction cascade and the calcium homeostasis in A. nidulans and N. crassa”; i-med Auslandsstipendium |
| 2006 | Visiting researcher at St. John's University, Department of Biological Sciences, Institute for Biotechnology, New York, Dr. D. Bartelt "Measurement of the intracellular calcium concentration in Aspergillus nidulans expressing the recombinant photoprotein aequorin"; 2 months; i-med Auslandsstipendium) |
| 2005 | Internship (six months) at the Technical University of Denmark (DTU), Centre for Microbial Biotechnology, Copenhagen, Prof. Jens Nielsen. Training in "Expression of recombinant proteins in yeast" |
Grants and fellowships
| 2021 | Talento 2021 programme of the University of Murcia, Spain to invite foreign researchers |
| 2020-2022 | Olorofim – Novel Antifungals (GZ 69272; D-155110-024-012) granted by f2G-the rare fungal disease company, Austria & UK |
| 2018/2019 | Fundacion Seneca (20617/IV/18); Regional Ministry of Employment, University and Enterprise, Murcia, Spain; Programme for mobility, collaboration and knowledge transfer: “Deciphering virulence traits of Mucor circinelloides by the use of bioluminescent reporter strains” |
| 2017 | EMBO 6856, short term fellowship: Cloning strategies in Mucor circinelloides (University of Murcia, Spain) |
| 2012-2015 | MUI-Start 2012092002: “Galleria mellonella as a host model to study invasive fungal infections due to Mucorales” |
| 2012-2014 | Gilead independent study grant (D-155110-024-011) “Galleria mellonella as a host model to study Mucorales infections and antifungal efficacy” |
| 2008 | EMBO ASTF 195.00-2008 (Edinburgh University, UK) ÖFG travel grant “internationale Kommunikation” (Edinburgh University, UK) |
| 2007 | "i-med Auslandsstipendium" (Edinburgh University, UK) |
| 2006 | "i-med Auslandsstipendium" (St. John´s University, New York) |
Co applicant/Project partner on (inter)national projects
Adenine-methylation of DNA as epigenetic marker in the control of mucormycosis (20897/PI/18I; Fundacion Seneca) to Prof. Victoriano Garre (2019-2022), project partner
Characterization of intrinsic azole resistance in mucormycetes (FWF- grant P32329-B) to Assoc. Prof. Dr. Michaela Lackner (2019-2023), co-applicant
Christian Doppler-Laboratory for fungal infections: avoid, find and treat (Christian-Doppler-Society) to Prof. Cornelia Lass-Flörl (2015-2020); project partner; leader of the module 1 “from bench to bedside, WP 1.1& 1.2, involved also in WP 1.3
Awards and Scholarships (selected)
| 2021 | Poster prize at the MYK21, Erlangen (online) |
| 2019 | DMykG Lecture, Göttingen, Germany ÖGMM price for best publication in basic mycological research |
| 2015 | Poster prize at the ISHAM meeting, Melbourne |
| 2012 | ÖFG travel award for research visit to the National University of Ireland Maynooth |
| 2011 | ECMM Young Investigators Travel Award and poster prize at TIMM 2011 ÖFG travel grant to participate in the annual meeting of the British Mycological Society in Exeter |
| 2010 | ÖFG and FEMS travel grant to participate in the 9th International Congress: The Biology of Fungi in Edinburgh, UK FEMS young scientist meeting grant to participate in the 10th European Conference on Fungal Genetics in Leiden, The Netherlands |
Additional academic activities
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Co-organizer (local committee) of the 16th ECFG (European Conference on Fungal Genetics) in 2023 |
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Organizer of the 1rst Mucormycete satellite meeting in the frame of ECFG 2023 |
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Co-organizer (local committee) of the Myk2022 in Wien (scientific meeting of the German & Austrian society of medical mycology); Organiser of the “Young Mycology course” in the frame of MYK2022 |
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Co-organizer, speaker and tutor of the FEBS 2020 Advanced Practical course „State-of-the-art alternative infection models to study molecular mechanisms of human fungal infections” |
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Co-organizer (local committee) of the Myk2018 in Innsbruck (scientific meeting of the German & Austrian society of medical mycology) |
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Guest Editor for the special issue “Fungal Pathogenesis” in Genes (MDPI) |
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Editorial Board member for Medical Mycology (2017-2020); Frontiers in Fungal Biology (2020-to date) |
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Section editor Current Fungal Infection reports (CFIR); section Advances in Diagnosis of Invasive Fungal Infections (2012-2014) |
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Peer reviewing activities on a regular basis |
| Medical Microbiology and Immunology (Springer) Applied Microbiology and Biotechnology (Springer) Antimicrobial Agents and Chemotherapy (ASM) Virulence (Taylor and Francies) Scientific Reports (Nature) Medical Mycology (Oxford Acamedic) Journal of Fungi (MDPI) Mycoses (Wiley-Blackwell) Molecules (MDPI) Genes (MDPI) Frontiers in Microbiology |
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Active membership in Societies |
| Austrian Society for Medical Microbiology (ÖGMM); Board Member German Speaking Society for Mycology (DMykG) International Society of Human and Animal Mycology (ISHAM) Austrian Society of Hygiene, Microbiology and Preventive Medicine (ÖGHMP) Austrian Association of Molecular Life Sciences and Biotechnology (ÖGMBT) |
Other career related activities
| 2021 - ongoing | Substitute Member of the Work council of the MUI |
| 10/2019-2020 | Member of the Work council of the MUI |
| 2017/2018 | Woods up Project, “KlasseForschung”, teaching program in high schools |
| 2016-2019 | Substitute Member of the Work council of the MUI |
| 07/08 2003 | Internship at Sandoz, Kundl, Austria; Quality assurance Microbiology |
| 07/08 2002 | Internship at Sandoz, Kundl, Austria; Quality assurance Microbiology |
Publications
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Teaching
