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Ulrike Binder

Ulrike BINDER logo-orcid
Priv.-Doz. Mag.Dr.rer.nat. PhD

Tel.: +43 (0)512 9003-70748
E-Mail: ulrike.binder@i-med.ac.at


Biographical sketch and research interests

Studies of Microbiology and Molecular Biology at the Leopold-Franzens-University, Innsbruck, Austria – Master and PhD in Microbiology; Internships at Technical University Denmark, University of Edinburgh, National Institute of Chemistry, Ljubljana, University of Murcia, Spain - Habilitation at the Medical University of Innsbruck for Microbiology
human fungal pathogens, Mucormycetes, Aspergillus spp., Candida spp., antifungal susceptibility and resistance, novel antifungal agents, mechanisms of resistance, alternative in vitro and in vivo models, Galleria mellonella, host-pathogen interactions, viruelnce traits, bioluminescent reporter strains, bioluminescent imaging

 

Current Position

Senior Scientist (permanent position)

 

Education

2019 Venia docendi/Habilitation for the subject Microbiology "Alternative models to study antifungal susceptibility and virulence of pathogenic molds"
2017
Completion of the "Helene Wastl Medizin Mentoring programme" of the MUI

2012 Diploma "CBS course on Medical Mycology"
2005 - 2009


Doctoral thesis at the Biocenter, Division of Molecular Biology, Medical University Innsbruck. "Characterization of the toxicity of the Penicillium chrysogenum antifungal protein PAF", passed with distinction

2003 - 2005

Master thesis at the Biocenter, Division of Molecular Biology, Medical University Innsbruck. "Characterisation of antifungal proteins secreted by aspergilli", passed with distinction

1999 - 2005 Studies of Biology/Microbiology at the Leopold-Franzens-University Innsbruck, Austria

 

Career History

Since 2020 Senior Scientist (permanent position) at the Institute of Hygiene and Medical Microbiology; group leader within the Mycology Unit of the Institute
2021 Research visit to the Department of Fungal Genetics, University of Murcia, Spain, collaboration with Prof. Victoriano Garre, “Genetic modification in Rhizopus microsporus”; Talento programme
2019 Venida docendi/Habilitation for the subject Microbiology “Alternative models to study antifungal susceptibility and virulence of pathogenic molds”
2015-2019 Senior Scientist/Postdoc (50%/50%) at the Institute of Hygiene and Medical Microbiology; group leader within the Mycology Unit of the Institute
2017 Visiting researcher at the Department of Fungal Genetics, University of Murcia, Spain, collaboration with Prof. Victoriano Garre, “Genetic modification in Mucor circinelloides”; EMBO fellowship
2015 Research visit at the Institute of Microbiology, CHUV Lausanne; Assoc.Prof. Dr. D. Sanglard. Training in molecular biological techniques to be applied in the Galleria mellonella model
2012 Research visit at the National University of Ireland Maynooth, Department of Biology, collaboration with Dr. Kevin Kavanagh; "Suitability and adaptation of the alternative in vivo model Galleria mellonella for A. terreus and Mucorales"
2011-2015 Postdoctoral research fellow/group leader at the Institute of Hygiene and Medical Microbiology
2009-2010 Postdoctoral research fellow at the Division of Molecular Biology, Biocenter, Innsbruck Medical University
2008/2009 Visiting researcher at the Institute of Cell Biology, University of Edinburgh, collaboration with Prof. Dr. ND Read. “The antifungal protein PAF disrupts calcium signalling in N. crassa”, EMBO fellowship
2007 Visiting researcher at the Institute of Cell Biology, University of Edinburgh. Collaboration with Prof. Dr. ND Read “The influence of antifungal proteins on the calcium signal transduction cascade and the calcium homeostasis in A. nidulans and N. crassa”; i-med Auslandsstipendium
2006 Visiting researcher at St. John's University, Department of Biological Sciences, Institute for Biotechnology, New York, Dr. D. Bartelt "Measurement of the intracellular calcium concentration in Aspergillus nidulans expressing the recombinant photoprotein aequorin"; 2 months; i-med Auslandsstipendium)
2005 Internship (six months) at the Technical University of Denmark (DTU), Centre for Microbial Biotechnology, Copenhagen, Prof. Jens Nielsen. Training in "Expression of recombinant proteins in yeast"

 

Grants and fellowships

2021 Talento 2021 programme of the University of Murcia, Spain to invite foreign researchers
2020-2022 Olorofim – Novel Antifungals (GZ 69272; D-155110-024-012) granted by f2G-the rare fungal disease company, Austria & UK
2018/2019 Fundacion Seneca (20617/IV/18); Regional Ministry of Employment, University and Enterprise, Murcia, Spain; Programme for mobility, collaboration and knowledge transfer: “Deciphering virulence traits of Mucor circinelloides by the use of bioluminescent reporter strains”
2017 EMBO 6856, short term fellowship: Cloning strategies in Mucor circinelloides (University of Murcia, Spain)
2012-2015 MUI-Start 2012092002: “Galleria mellonella as a host model to study invasive fungal infections due to Mucorales”
2012-2014 Gilead independent study grant (D-155110-024-011) “Galleria mellonella as a host model to study Mucorales infections and antifungal efficacy”
2008 EMBO ASTF 195.00-2008 (Edinburgh University, UK)
ÖFG travel grant “internationale Kommunikation” (Edinburgh University, UK)
2007 "i-med Auslandsstipendium" (Edinburgh University, UK)
2006 "i-med Auslandsstipendium" (St. John´s University, New York)

 

Co applicant/Project partner on (inter)national projects

Adenine-methylation of DNA as epigenetic marker in the control of mucormycosis (20897/PI/18I; Fundacion Seneca) to Prof. Victoriano Garre (2019-2022), project partner

Characterization of intrinsic azole resistance in mucormycetes (FWF- grant P32329-B) to Assoc. Prof. Dr. Michaela Lackner (2019-2023), co-applicant

Christian Doppler-Laboratory for fungal infections: avoid, find and treat (Christian-Doppler-Society) to Prof. Cornelia Lass-Flörl (2015-2020); project partner; leader of the module 1 “from bench to bedside, WP 1.1& 1.2, involved also in WP 1.3

 

Awards and Scholarships (selected)

2021 Poster prize at the MYK21, Erlangen (online)
2019 DMykG Lecture, Göttingen, Germany
ÖGMM price for best publication in basic mycological research
2015 Poster prize at the ISHAM meeting, Melbourne
2012 ÖFG travel award for research visit to the National University of Ireland Maynooth
2011 ECMM Young Investigators Travel Award and poster prize at TIMM 2011
ÖFG travel grant to participate in the annual meeting of the British Mycological Society in Exeter
2010 ÖFG and FEMS travel grant to participate in the 9th International Congress:
The Biology of Fungi in Edinburgh, UK
FEMS young scientist meeting grant to participate in the
10th European Conference on Fungal Genetics in Leiden, The Netherlands

 

Additional academic activities

Co-organizer (local committee) of the 16th ECFG (European Conference on Fungal Genetics) in 2023
Organizer of the 1rst Mucormycete satellite meeting in the frame of ECFG 2023
Co-organizer (local committee) of the Myk2022 in Wien (scientific meeting of the German & Austrian society of medical mycology); Organiser of the “Young Mycology course” in the frame of MYK2022
Co-organizer, speaker and tutor of the FEBS 2020 Advanced Practical course „State-of-the-art alternative infection models to study molecular mechanisms of human fungal infections” 
Co-organizer (local committee) of the Myk2018 in Innsbruck (scientific meeting of the German & Austrian society of medical mycology)
Guest Editor for the special issue “Fungal Pathogenesis” in Genes (MDPI)
Editorial Board member for Medical Mycology (2017-2020); Frontiers in Fungal Biology (2020-to date)
Section editor Current Fungal Infection reports (CFIR); section Advances in Diagnosis of Invasive Fungal Infections (2012-2014)
Peer reviewing activities on a regular basis
  Medical Microbiology and Immunology (Springer)
Applied Microbiology and Biotechnology (Springer)
Antimicrobial Agents and Chemotherapy (ASM)
Virulence (Taylor and Francies)
Scientific Reports (Nature)
Medical Mycology (Oxford Acamedic)
Journal of Fungi (MDPI)
Mycoses (Wiley-Blackwell)
Molecules (MDPI)
Genes (MDPI)
Frontiers in Microbiology
Active membership in Societies
  Austrian Society for Medical Microbiology (ÖGMM); Board Member
German Speaking Society for Mycology (DMykG)
International Society of Human and Animal Mycology (ISHAM)
Austrian Society of Hygiene, Microbiology and Preventive Medicine (ÖGHMP)
Austrian Association of Molecular Life Sciences and Biotechnology (ÖGMBT)

 

Other career related activities 

2021 - ongoing Substitute Member of the Work council of the MUI
10/2019-2020 Member of the Work council of the MUI
2017/2018 Woods up Project, “KlasseForschung”, teaching program in high schools
2016-2019 Substitute Member of the Work council of the MUI
07/08 2003 Internship at Sandoz, Kundl, Austria; Quality assurance Microbiology
07/08 2002 Internship at Sandoz, Kundl, Austria; Quality assurance Microbiology

 

Publications

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Teaching

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