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Publications - Institute of Molecular Biology

 

2020

  • Bauer, Ingo; Gross, Silke; Merschak, Petra; Kremser, Leopold; Karahoda, Betim; Bayram, Ozlem Sarikaya; Abt, Beate; Binder, Ulrike; Gsaller, Fabio; Lindner, Herbert; Bayram, Ozgur; Brosch, Gerald; Graessle, Stefan: RcLS2F-A Novel Fungal Class 1 KDAC Co-repressor Complex in Aspergillus nidulans. FRONTIERS IN MICROBIOLOGY. 2020; 11(S); 43.
  • Birstonas, Lukas; Dallemulle, Alex; Lopez-Berges, Manuel S.; Jacobsen, Ilse D.; Offterdinger, Martin; Abt, Beate; Strassburger, Maria; Bauer, Ingo; Schmidt, Oliver; Sarg, Bettina; Lindner, Herbert; Haas, Hubertus; Gsaller, Fabio: Multiplex Genetic Engineering Exploiting Pyrimidine Salvage Pathway-Based Endogenous Counterselectable Markers. MBIO. 2020; 11(2); e00230-20.
  • Bobkov, Georg O. M.; Huang, Anming; van den Berg, Sebastiaan J. W.; Mitra, Sreyoshi; Anselm, Eduard; Lazou, Vasiliki; Schunter, Sarah; Feederle, Regina; Imhof, Axel; Lusser, Alexandra; Jansen, Lars E. T.; Heun, Patrick: Spt6 is a maintenance factor for centromeric CENP-A. NATURE COMMUNICATIONS. 2020; 11(1); 2919.
  • Cruz, Ytallo W. G.; Vieira, Yago A.; Vilar, Debora S.; Torres, Nadia H.; Aguiar, Mario M.; Cavalcanti, Eliane B.; Americo-Pinheiro, Juliana H. P.; Soriano, Renato N.; Bharagava, Ram N.; Lima, Alvaro S.; Ferreira, Luiz F. R.: Pulp wash: a new source for production of ligninolytic enzymes and biomass and its toxicological evaluation after biological treatment. ENVIRONMENTAL TECHNOLOGY. 2020; 41(14); 1837-1847.
  • Dietl, Anna-Maria; Binder, Ulrike; Bauer, Ingo; Shadkchan, Yana; Osherov, Nir; Haas, Hubertus: Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of Aspergillus fumigatus. GENES. 2020; 11(4); 423.
  • Furukawa, Takanori; Scheven, Mareike Thea; Misslinger, Matthias; Zhao, Can; Hoefgen, Sandra; Gsaller, Fabio; Lau, Jeffrey; Joechl, Christoph; Donaldson, Ian; Valiante, Vito; Brakhage, Axel A.; Bromley, Michael J.; Haas, Hubertus; Hortschansky, Peter: The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition. NUCLEIC ACIDS RESEARCH. 2020; 48(7); 3567-3590.
  • Gaspar-Cordeiro, A.; da Silva, S.; Aguiar, M.; Rodrigues-Pousada, C.; Haas, H.; Lima, L. M. P.; Pimentel, C.: A copper(II)-binding triazole derivative with ionophore properties is active against Candida spp. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2020; 25(8); 1117-1128.
  • Gasser, Catherina; Delazer, Isabel; Neuner, Eva; Pascher, Katharina; Brillet, Karl; Klotz, Sarah; Trixl, Lukas; Himmelstoss, Maximilian; Ennifar, Eric; Rieder, Dietmar; Lusser, Alexandra; Micura, Ronald: Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2020; 59(17); 6881-6886.
  • Habeler, Matthias; Lindner, Herbert H.; Redl, Bernhard: A role of heparan sulphate proteoglycan in the cellular uptake of lipocalins ss-lactoglobulin and allergen Fel d 4. BIOLOGICAL CHEMISTRY. 2020; 401(9); 1081-1092.
  • Habeler, Matthias; Redl, Bernhard: Phage-display reveals interaction of lipocalin allergen Can f 1 with a peptide resembling the antigen binding region of a human γδT-cell receptor. BIOLOGICAL CHEMISTRY. 2020; [Epub ahead of print];
  • Haselwandter, Kurt; Haas, Hubertus; Haeninger, Gerlinde; Winkelmann, Guenther: Siderophores in plant root tissue: Tagetes patula nana colonized by the arbuscular mycorrhizal fungus Gigaspora margarita. BIOMETALS. 2020; 33(2-3); 137-146.
  • Holzknecht, Jeanett; Kuehbacher, Alexander; Papp, Csaba; Farkas, Attila; Varadi, Gyorgyi; Marcos, Jose F.; Manzanares, Paloma; Toth, Gabor K.; Galgoczy, Laszlo; Marx, Florentine: The Penicillium chrysogenum Q176 Antimicrobial Protein PAFC Effectively Inhibits the Growth of the Opportunistic Human Pathogen Candida albicans. JOURNAL OF FUNGI. 2020; 6(3); 141.
  • Hortschansky, Peter; Misslinger, Matthias; Moerl, Jasmin; Gsaller, Fabio; Bromley, Michael J.; Brakhage, Axel A.; Groll, Michael; Haas, Hubertus; Huber, Eva M.: Structural basis of HapE(P88L)-linked antifungal triazole resistance in Aspergillus fumigatus. LIFE SCIENCE ALLIANCE. 2020; 3(7); e202000729.
  • Hoser, Simon M.; Hoffmann, Anne; Meindl, Andreas; Gamper, Maximilian; Fallmann, Joerg; Bernhart, Stephan H.; Mueller, Lisa; Ploner, Melanie; Misslinger, Matthias; Kremser, Leopold; Lindner, Herbert; Geley, Stephan; Schaal, Heiner; Stadler, Peter F.; Huettenhofer, Alexander: Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing. GENOME BIOLOGY. 2020; 21(1); 299.
  • Junior, Joberson Alves; Vieira, Yago Araujo; Cruz, Ianny Andrade; da Silva Vilar, Débora; Aguiar, Mario M; Torres, Nádia Hortense; Bharagava, Ram Naresh; Lima, Álvaro Silva; de Souza, Ranyere Lucena; Romanholo Ferreira, Luiz Fernando: Sequential degradation of raw vinasse by a laccase enzyme producing fungus Pleurotus sajor-caju and its ATPS purification. BIOTECHNOLOGY REPORTS. 2020; 25; e00411.
  • Lusser, Alexandra; Gasser, Catherina; Trixl, Lukas; Piatti, Paolo; Delazer, Isabel; Rieder, Dietmar; Bashin, Jeffrey; Riml, Christian; Amort, Thomas; Micura, Ronald: Thiouridine-to-Cytidine Conversion Sequencing (TUC-Seq) to Measure mRNA Transcription and Degradation Rates. METHODS IN MOLECULAR BIOLOGY. 2020; 2062; 191-211.
  • Nazik, Hasan; Sass, Gabriele; Ansari, Shajia R.; Ertekin, Reyhan; Haas, Hubertus; Deziel, Eric; Stevens, David A.: Novel intermicrobial molecular interaction: Pseudomonas aeruginosa Quinolone Signal (PQS) modulates Aspergillus fumigatus response to iron. MICROBIOLOGY-SGM. 2020; 166(1); 44-55.
  • Pahlow, Susanne; Orasch, Thomas; Zukovskaja, Olga; Bocklitz, Thomas; Haas, Hubertus; Weber, Karina: Rapid detection of the aspergillosis biomarker triacetylfusarinine C using interference-enhanced Raman spectroscopy. ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2020; 412(24); 6351-6360.
  • Pfister, Joachim; Bata, Roland; Hubmann, Isabella; Hormann, Anton Amadeus; Gsaller, Fabio; Haas, Hubertus; Decristoforo, Clemens: Siderophore Scaffold as Carrier for Antifungal Peptides in Therapy of Aspergillus fumigatus Infections. JOURNAL OF FUNGI. 2020; 6(4); 367.
  • Pfister, Joachim; Lichius, Alexander; Summer, Dominik; Haas, Hubertus; Kanagasundaram, Thines; Kopka, Klaus; Decristoforo, Clemens: Live-cell imaging with Aspergillus fumigatus-specific fluorescent siderophore conjugates. SCIENTIFIC REPORTS. 2020; 10(1); 15519.
  • Pfister, Joachim; Summer, Dominik; Petrik, Milos; Khoylou, Marta; Lichius, Alexander; Kaeopookum, Piriya; Kochinke, Laurin; Orasch, Thomas; Haas, Hubertus; Decristoforo, Clemens: Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, Ga-68-Labelled Siderophores. BIOMOLECULES. 2020; 10(2); 168.
  • Summer, Dominik; Petrik, Milos; Mayr, Sonja; Hermann, Martin; Kaeopookum, Piriya; Pfister, Joachim; Klingler, Maximilian; Rangger, Christine; Haas, Hubertus; Decristoforo, Clemens: Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C-Proof of Concept. MOLECULES. 2020; 25(9); 2123.
  • Toth, Liliana; Boros, Eva; Poor, Peter; Ordog, Attila; Kele, Zoltan; Varadi, Gyorgyi; Holzknecht, Jeanett; Bratschun-Khan, Doris; Nagy, Istvan; Toth, Gabor K.; Rakhely, Gabor; Marx, Florentine; Galgoczy, Laszlo: The potential use of thePenicillium chrysogenumantifungal protein PAF, the designed variant PAF(opt)and its gamma-core peptide P gamma(opt)in plant protection. MICROBIAL BIOTECHNOLOGY. 2020; 13(5); 1403-1414.
  • Toth, Liliana; Varadi, Gyorgyi; Boros, Eva; Borics, Attila; Ficze, Hargita; Nagy, Istvan; Toth, Gabor K.; Rakhely, Gabor; Marx, Florentine; Galgoczy, Laszlo: Biofungicidal Potential of Neosartorya (Aspergillus) Fischeri Antifungal Protein NFAP and Novel Synthetic gamma-Core Peptides. FRONTIERS IN MICROBIOLOGY. 2020; 11(S); 820.
  • Huber, A.; Galgoczy, L.; Varadi, G.; Holzknecht, J.; Kakar, A.; Malanovic, N.; Leber, R.; Koch, J.; Keller, M. A.; Batta, G.; Toth, G. K.; Marx, F.: Two small, cysteine-rich and cationic antifungal proteins from Penicillium chrysogenum: A comparative study of PAF and PAFB. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2020; 1862(8); 183246.
  • Petrik, Milos; Pfister, Joachim; Misslinger, Matthias; Decristoforo, Clemens; Haas, Hubertus: Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections-Current Status and Future Perspectives. JOURNAL OF FUNGI. 2020; 6(2); 73.
  • Yap, Annie; Misslinger, Matthias; Haas, Hubertus: Absent regulation of iron acquisition by the copper regulator Mac1 in A. fumigatus. BIOCHEMICAL JOURNAL. 2020; 477(16); 2967-2970.

2019

  • Huber A, Lerchster H, Marx F. Nutrient Excess Triggers the Expression of the Penicillium chrysogenum Antifungal Protein PAFB. Microorganisms. 2019 Dec 4;7(12). pii: E654. doi: 10.3390/microorganisms7120654. PubMed PMID: 31817241; PubMed Central PMCID: PMC6956099.

 

  • Galgóczy L, Yap A, Marx F. Cysteine-Rich Antifungal Proteins from Filamentous Fungi are Promising Bioactive Natural Compounds in Anti-Candida Therapy. Isr J Chem. 2019 May;59(5):360-370. doi: 10.1002/ijch.201800168. Epub 2019 Feb 20. Review. PubMed PMID: 31680702; PubMed Central PMCID: PMC6813639.

 

  • Huber A, Oemer G, Malanovic N, Lohner K, Kovács L, Salvenmoser W, Zschocke J, Keller MA, Marx F. Membrane Sphingolipids Regulate the Fitness and Antifungal Protein Susceptibility of Neurospora crassa. Front Microbiol. 2019 Apr 11;10:605. doi: 10.3389/fmicb.2019.00605. eCollection 2019. PubMed PMID: 31031714; PubMed Central PMCID: PMC6471014.

 

  • Hajdu D, Huber A, Czajlik A, Tóth L, Kele Z, Kocsubé S, Fizil Á, Marx F, Galgóczy L, Batta G. Solution structure and novel insights into phylogeny and mode of action of the Neosartorya (Aspergillus) fischeri antifungal protein (NFAP). Int J Biol Macromol. 2019 May 15;129:511-522. doi: 10.1016/j.ijbiomac.2019.02.016. Epub 2019 Feb 7. PubMed PMID: 30738898.

 

  • Galgóczy L, Marx F. Do Antimicrobial Proteins Contribute to Overcoming the Hidden Antifungal Crisis at the Dawn of a Post-Antibiotic Era? Microorganisms. 2019 Jan 11;7(1). pii: E16. doi: 10.3390/microorganisms7010016. PubMed PMID: 30641886; PubMed Central PMCID: PMC6352135.

 

  • Kovács R, Holzknecht J, Hargitai Z, Papp C, Farkas A, Borics A, Tóth L, Váradi G, Tóth GK, Kovács I, Dubrac S, Majoros L, Marx F, Galgóczy L. In Viv Applicability of Neosartorya fischeri Antifungal Protein 2 (NFAP2) in Treatment of Vulvovaginal Candidiasis. Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01777-18. doi: 10.1128/AAC.01777-18. Print 2019 Feb. PubMed PMID: 30478163; PubMed Central PMCID: PMC6355578.

 

  • Huang A, Kremser L, Schuler F, Wilflingseder D, Lindner H, Geley S, Lusser A. Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading. Nucleic Acids Res. 2019 Nov 18;47(20):10754-10770. doi: 10.1093/nar/gkz809. PubMed PMID: 31535131; PubMed Central PMCID: PMC6847487.

 

  • Ordu O, Lusser A, Dekker NH. DNA Sequence Is a Major Determinant of Tetrasome Dynamics. Biophys J. 2019 Dec 3;117(11):2217-2227. doi: 10.1016/j.bpj.2019.07.055. Epub 2019 Aug 21. PubMed PMID: 31521330; PubMed Central PMCID: PMC6895708.

 

  • Trixl L, Lusser A. Publisher Correction: RNA modification: Getting a hold on cytosine methylation in mRNA. Nat Struct Mol Biol. 2019 Jun;26(6):526. doi: 10.1038/s41594-019-0247-5. PubMed PMID: 31089246.

 

  • Trixl L, Lusser A. Getting a hold on cytosine methylation in mRNA. Nat Struct Mol Biol. 2019 May;26(5):339-340. doi: 10.1038/s41594-019-0217-y. Erratum in: Nat Struct Mol Biol. 2019 Jun;26(6):526. PubMed PMID: 31061523.

 

  • Schoberleitner I, Mutti A, Sah A, Wille A, Gimeno-Valiente F, Piatti P, Kharitonova M, Torres L, López-Rodas G, Liu JJ, Singewald N, Schwarzer C, Lusser A. Role for Chromatin Remodeling Factor Chd1 in Learning and Memory. Front Mol Neurosci. 2019 Jan 23;12:3. doi: 10.3389/fnmol.2019.00003. eCollection 2019. PubMed PMID: 30728766; PubMed Central PMCID: PMC6351481.

 

  • Trixl L, Rieder D, Amort T, Lusser A. Bisulfite Sequencing of RNA for Transcriptome-Wide Detection of 5-Methylcytosine. Methods Mol Biol. 2019;1870:1-21. doi: 10.1007/978-1-4939-8808-2_1. PubMed PMID: 30539543.

 

  • Bauer I, Misslinger M, Shadkchan Y, Dietl AM, Petzer V, Orasch T, Abt B, Graessle S, Osherov N, Haas H. The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus. Front Microbiol. 2019 Dec 4;10:2773. doi: 10.3389/fmicb.2019.02773. eCollection 2019. PubMed PMID: 31866965; PubMed Central PMCID: PMC6905131.

 

  • Bauer I, Lechner L, Pidroni A, Petrone AM, Merschak P, Lindner H, Kremser L, Graessle S, Golderer G, Allipour S, Brosch G. Type I and II PRMTs regulate catabolic as well as detoxifying processes in Aspergillus nidulans. Fungal Genet Biol. 2019 Aug;129:86-100. doi: 10.1016/j.fgb.2019.05.006. Epub 2019 May 28. PubMed PMID: 31145992; PubMed Central PMCID: PMC6837890.

 

  • Bauer I, Pidroni A, Bayram Ö, Brosch G, Graessle S. Single-Step Enrichment of a TAP-Tagged Histone Deacetylase of the Filamentous Fungus Aspergillus nidulans for Enzymatic Activity Assay. J Vis Exp. 2019 May 1;(147). doi: 10.3791/59527. PubMed PMID: 31107465.

 

  • Nazik H, Sass G, Ansari SR, Ertekin R, Haas H, Déziel E, Stevens DA. Novel intermicrobial molecular interaction: Pseudomonas aeruginosa Quinolone Signal (PQS) modulates Aspergillus fumigatus response to iron. Microbiology. 2020 Jan;166(1):44-55. doi: 10.1099/mic.0.000858. Epub 2019 Nov 15. PubMed PMID: 31778108.

 

  • Orasch T, Dietl AM, Shadkchan Y, Binder U, Bauer I, Lass-Flörl C, Osherov N, Haas H. The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus. Virulence. 2019 Dec;10(1):925-934. doi: 10.1080/21505594.2019.1682760. PubMed PMID: 31694453; PubMed Central PMCID: PMC6844326.

 

  • Kaeopookum P, Petrik M, Summer D, Klinger M, Zhai C, Rangger C, Haubner R, Haas H, Hajduch M, Decristoforo C. Comparison of (68)Ga-labeled RGD mono- and multimers based on a clickable siderophore-based scaffold. Nucl Med Biol. 2019 Nov - Dec;78-79:1-10. doi: 10.1016/j.nucmedbio.2019.09.002. Epub 2019 Oct 25. PubMed PMID: 31678781.

 

  • Misslinger M, Scheven MT, Hortschansky P, López-Berges MS, Heiss K, Beckmann N, Heigl T, Hermann M, Krüger T, Kniemeyer O, Brakhage AA, Haas H. The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus. PLoS Genet. 2019 Sep 16;15(9):e1008379. doi: 10.1371/journal.pgen.1008379. eCollection 2019 Sep. PubMed PMID: 31525190; PubMed Central PMCID: PMC6762210.

 

  • Dietl AM, Misslinger M, Aguiar MM, Ivashov V, Teis D, Pfister J, Decristoforo C, Hermann M, Sullivan SM, Smith LR, Haas H. The Siderophore Transporter Sit1 Determines Susceptibility to the Antifungal VL-2397. Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e00807-19. doi: 10.1128/AAC.00807-19. Print 2019 Oct. PubMed PMID: 31405865; PubMed Central PMCID: PMC6761561.

 

  • Petzer V, Wermke M, Tymoszuk P, Wolf D, Seifert M, Ovaçin R, Berger S, Orth-Höller D, Loacker L, Weiss G, Haas H, Platzbecker U, Theurl I. Enhanced labile plasma iron in hematopoietic stem cell transplanted patients promotes Aspergillus outgrowth. Blood Adv. 2019 Jun 11;3(11):1695-1700. doi: 10.1182/bloodadvances.2019000043. PubMed PMID: 31167821; PubMed Central PMCID: PMC6560355.

 

  • Sass G, Ansari SR, Dietl AM, Déziel E, Haas H, Stevens DA. Intermicrobial interaction: Aspergillus fumigatus siderophores protect against competition by Pseudomonas aeruginosa. PLoS One. 2019 May 8;14(5):e0216085. doi: 10.1371/journal.pone.0216085. eCollection 2019. PubMed PMID: 31067259; PubMed Central PMCID: PMC6505954.

 

  • Zhai C, He S, Ye Y, Rangger C, Kaeopookum P, Summer D, Haas H, Kremser L, Lindner H, Foster J, Sosabowski J, Decristoforo C. Rational Design, Synthesis and Preliminary Evaluation of Novel Fusarinine C-Based Chelators for Radiolabeling with Zirconium-89. Biomolecules. 2019 Mar 6;9(3). pii: E91. doi: 10.3390/biom9030091. PubMed PMID: 30845658; PubMed Central PMCID: PMC6468543.

 

  • Kaeopookum P, Summer D, Pfister J, Orasch T, Lechner BE, Petrik M, Novy Z, Matuszczak B, Rangger C, Haas H, Decristoforo C. Modifying the Siderophore Triacetylfusarinine C for Molecular Imaging of Fungal Infection. Mol Imaging Biol. 2019 Dec;21(6):1097-1106. doi: 10.1007/s11307-019-01325-6. PubMed PMID: 30838551; PubMed Central PMCID: PMC6877352.

 

  • Sass G, Nazik H, Penner J, Shah H, Ansari SR, Clemons KV, Groleau MC, Dietl AM, Visca P, Haas H, Déziel E, Stevens DA. Aspergillus-Pseudomonas interaction, relevant to competition in airways. Med Mycol. 2019 Apr 1;57(Supplement_2):S228-S232. doi: 10.1093/mmy/myy087. Review. PubMed PMID: 30816973.

 

  • Kenno S, Speth C, Rambach G, Binder U, Chatterjee S, Caramalho R, Haas H, Lass-Flörl C, Shaughnessy J, Ram S, Gow NAR, Orth-Höller D, Würzner R. Candida albicans Factor H Binding Molecule Hgt1p - A Low Glucose-Induced Transmembrane Protein Is Trafficked to the Cell Wall and Impairs Phagocytosis and Killing by Human Neutrophils. Front Microbiol. 2019 Jan 15;9:3319. doi: 10.3389/fmicb.2018.03319. eCollection 2018. PubMed PMID: 30697200; PubMed Central PMCID: PMC6340940.

 

  • Steger M, Bermejo-Jambrina M, Yordanov T, Wagener J, Brakhage AA, Pittl V, Huber LA, Haas H, Lass-Flörl C, Posch W, Wilflingseder D. β-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells. Virulence. 2019 Dec;10(1):957-969. doi: 10.1080/21505594.2018.1528843. Epub 2018 Oct 29. PubMed PMID: 30372658.

 

2018

  • Waldner A, Dassati S, Redl B, Smania N, Gandolfi M. Apolipoprotein D Concentration in Human Plasma during Aging and in Parkinson's Disease: A Cross-Sectional Study. Parkinsons Dis. 2018 Mar 26;2018:3751516. doi: 10.1155/2018/3751516. eCollection 2018. PubMed PMID: 29780571; PubMed Central PMCID: PMC5892211.

 

  • Garrigues S, Gandía M, Castillo L, Coca M, Marx F, Marcos JF, Manzanares P. Three Antifungal Proteins From Penicillium expansum: Different Patterns of Production and Antifungal Activity. Front Microbiol. 2018 Oct 5;9:2370. doi: 10.3389/fmicb.2018.02370. eCollection 2018. PubMed PMID: 30344516; PubMed Central PMCID: PMC6182064.

 

  • Fizil Á, Sonderegger C, Czajlik A, Fekete A, Komáromi I, Hajdu D, Marx F, Batta G. Calcium binding of the antifungal protein PAF: Structure, dynamics and function aspects by NMR and MD simulations. PLoS One. 2018 Oct 15;13(10):e0204825. doi: 10.1371/journal.pone.0204825. eCollection 2018. PubMed PMID: 30321182; PubMed Central PMCID: PMC6188699.

 

  • Sonderegger C, Váradi G, Galgóczy L, Kocsubé S, Posch W, Borics A, Dubrac S, Tóth GK, Wilflingseder D, Marx F. The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF. Front Microbiol. 2018 Jul 20;9:1655. doi: 10.3389/fmicb.2018.01655. eCollection 2018. PubMed PMID: 30079061; PubMed Central PMCID: PMC6062912.

 

  • Tóth L, Váradi G, Borics A, Batta G, Kele Z, Vendrinszky Á, Tóth R, Ficze H, Tóth GK, Vágvölgyi C, Marx F, Galgóczy L. Anti-Candidal Activity and Functional Mapping of Recombinant and Synthetic Neosartorya fischeri Antifungal Protein 2 (NFAP2). Front Microbiol. 2018 Mar 7;9:393. doi: 10.3389/fmicb.2018.00393. eCollection 2018. PubMed PMID: 29563903; PubMed Central PMCID: PMC5845869.

 

  • Huber A, Hajdu D, Bratschun-Khan D, Gáspári Z, Varbanov M, Philippot S, Fizil Á, Czajlik A, Kele Z, Sonderegger C, Galgóczy L, Bodor A, Marx F, Batta G. New Antimicrobial Potential and Structural Properties of PAFB: A Cationic, Cysteine-Rich Protein from Penicillium chrysogenum Q176. Sci Rep. 2018 Jan 29;8(1):1751. doi: 10.1038/s41598-018-20002-2. PubMed PMID: 29379111; PubMed Central PMCID: PMC5788923.

 

  • Neuner E, Frener M, Lusser A, Micura R. Superior cellular activities of azido- over amino-functionalized ligands for engineered preQ(1) riboswitches in E.coli. RNA Biol. 2018;15(10):1376-1383. doi: 10.1080/15476286.2018.1534526. Epub 2018 Oct 26. PubMed PMID: 30332908; PubMed Central PMCID: PMC6284575.

 

  • Trixl L, Lusser A. The dynamic RNA modification 5-methylcytosine and its emerging role as an epitranscriptomic mark. Wiley Interdiscip Rev RNA. 2019 Jan;10(1):e1510. doi: 10.1002/wrna.1510. Epub 2018 Oct 11. Review. PubMed PMID: 30311405; PubMed Central PMCID: PMC6492194.

 

  • Ordu O, Kremser L, Lusser A, Dekker NH. Modification of the histone tetramer at the H3-H3 interface impacts tetrasome conformations and dynamics. J Chem Phys. 2018 Mar 28;148(12):123323. doi: 10.1063/1.5009100. PubMed PMID: 29604863.

 

  • Gsaller F, Furukawa T, Carr PD, Rash B, Jöchl C, Bertuzzi M, Bignell EM, Bromley MJ. Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus. Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e02593-17. doi: 10.1128/AAC.02593-17. Print 2018 Jun. PubMed PMID: 29610197; PubMed Central PMCID: PMC5971587.

 

  • Pidroni A, Faber B, Brosch G, Bauer I, Graessle S. A Class 1 Histone Deacetylase as Major Regulator of Secondary Metabolite Production in Aspergillus nidulans. Front Microbiol. 2018 Sep 19;9:2212. doi: 10.3389/fmicb.2018.02212. eCollection 2018. Erratum in: Front Microbiol. 2018 Nov 09;9:2714. PubMed PMID: 30283426; PubMed Central PMCID: PMC6156440.

 

  • Dietl AM, Binder U, Shadkchan Y, Osherov N, Haas H. Siroheme Is Essential for Assimilation of Nitrate and Sulfate as Well as Detoxification of Nitric Oxide but Dispensable for Murine Virulence of Aspergillus fumigatus. Front Microbiol. 2018 Nov 12;9:2615. doi: 10.3389/fmicb.2018.02615. eCollection 2018. PubMed PMID: 30483221; PubMed Central PMCID: PMC6240589.

 

  • Misslinger M, Lechner BE, Bacher K, Haas H. Iron-sensing is governed by mitochondrial, not by cytosolic iron-sulfur cluster biogenesis in Aspergillus fumigatus. Metallomics. 2018 Nov 14;10(11):1687-1700. doi: 10.1039/c8mt00263k. PubMed PMID: 30395137; PubMed Central PMCID: PMC6250123.

 

  • Long N, Orasch T, Zhang S, Gao L, Xu X, Hortschansky P, Ye J, Zhang F, Xu K, Gsaller F, Straßburger M, Binder U, Heinekamp T, Brakhage AA, Haas H, Lu L. The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus. PLoS Genet. 2018 Oct 26;14(10):e1007762. doi: 10.1371/journal.pgen.1007762. eCollection 2018 Oct. PubMed PMID: 30365497; PubMed Central PMCID: PMC6221358.

 

  • Petrik M, Umlaufova E, Raclavsky V, Palyzova A, Havlicek V, Haas H, Novy Z, Dolezal D, Hajduch M, Decristoforo C. Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography. Sci Rep. 2018 Oct 24;8(1):15698. doi: 10.1038/s41598-018-33895-w. PubMed PMID: 30356077; PubMed Central PMCID: PMC6200719.

 

  • Hoenigl M, Orasch T, Faserl K, Prattes J, Loeffler J, Springer J, Gsaller F, Reischies F, Duettmann W, Raggam RB, Lindner H, Haas H. Triacetylfusarinine C: A urine biomarker for diagnosis of invasive aspergillosis. J Infect. 2019 Feb;78(2):150-157. doi: 10.1016/j.jinf.2018.09.006. Epub 2018 Sep 26. PubMed PMID: 30267801; PubMed Central PMCID: PMC6361682.

 

  • Ecker F, Haas H, Groll M, Huber EM. Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14624-14629. doi: 10.1002/anie.201807093. Epub 2018 Aug 27. PubMed PMID: 30070018.

 

  • Summer D, Kroess A, Woerndle R, Rangger C, Klingler M, Haas H, Kremser L, Lindner HH, von Guggenberg E, Decristoforo C. Multimerization results in formation of re-bindable metabolites: A proof of concept study with FSC-based minigastrin imaging probes targeting CCK2R expression. PLoS One. 2018 Jul 30;13(7):e0201224. doi: 10.1371/journal.pone.0201224. eCollection 2018. PubMed PMID: 30059514; PubMed Central PMCID: PMC6066219.

 

  • Jahreis S, Böttcher S, Hartung S, Rachow T, Rummler S, Dietl AM, Haas H, Walther G, Hochhaus A, von Lilienfeld-Toal M. Human MAIT cells are rapidly activated by Aspergillus spp. in an APC-dependent manner. Eur J Immunol. 2018 Oct;48(10):1698-1706. doi: 10.1002/eji.201747312. Epub 2018 Aug 13. PubMed PMID: 30059139.

 

  • Dietl AM, Meir Z, Shadkchan Y, Osherov N, Haas H. Riboflavin and pantothenic acid biosynthesis are crucial for iron homeostasis and virulence in the pathogenic mold Aspergillus fumigatus. Virulence. 2018;9(1):1036-1049. doi: 10.1080/21505594.2018.1482181. PubMed PMID: 30052132; PubMed Central PMCID: PMC6068542.

 

  • Van Dijck P, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, Espinel-Ingroff A, Filler SG, Ghannoum M, Gow NAR, Haas H, Jabra-Rizk MA, Johnson EM, Lockhart SR, Lopez-Ribot JL, Maertens J, Munro CA, Nett JE, Nobile CJ, Pfaller MA, Ramage G, Sanglard D, Sanguinetti M, Spriet I, Verweij PE, Warris A, Wauters J, Yeaman MR, Zaat SAJ, Thevissen K. Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microb Cell. 2018 Jun 14;5(7):300-326. doi: 10.15698/mic2018.07.638. Review. PubMed PMID: 29992128; PubMed Central PMCID: PMC6035839.

 

  • Summer D, Rangger C, Klingler M, Laverman P, Franssen GM, Lechner BE, Orasch T, Haas H, von Guggenberg E, Decristoforo C. Exploiting the Concept of Multivalency with (68)Ga- and (89)Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression. Contrast Media Mol Imaging. 2018 Apr 10;2018:3171794. doi: 10.1155/2018/3171794. eCollection 2018. PubMed PMID: 29849512; PubMed Central PMCID: PMC5914118.

 

  • Kurucz V, Krüger T, Antal K, Dietl AM, Haas H, Pócsi I, Kniemeyer O, Emri T. Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion. BMC Genomics. 2018 May 10;19(1):357. doi: 10.1186/s12864-018-4730-x. PubMed PMID: 29747589; PubMed Central PMCID: PMC5946477.

 

  • Hsu JL, Manouvakhova OV, Clemons KV, Inayathullah M, Tu AB, Sobel RA, Tian A, Nazik H, Pothineni VR, Pasupneti S, Jiang X, Dhillon GS, Bedi H, Rajadas J, Haas H, Aurelian L, Stevens DA, Nicolls MR. Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation. Sci Transl Med. 2018 Feb 21;10(429). pii: eaag2616. doi: 10.1126/scitranslmed.aag2616. PubMed PMID: 29467298; PubMed Central PMCID: PMC5841257.

 

2017

  • Garrigues S, Gandía M, Popa C, Borics A, Marx F, Coca M, Marcos JF, Manzanares P. Efficient production and characterization of the novel and highly active antifungal protein AfpB from Penicillium digitatum. Sci Rep. 2017 Nov 7;7(1):14663. doi: 10.1038/s41598-017-15277-w. PubMed PMID: 29116156; PubMed Central PMCID: PMC5677034.

 

  • Galgóczy L, Borics A, Virágh M, Ficze H, Váradi G, Kele Z, Marx F. Structural determinants of Neosartorya fischeri antifungal protein (NFAP) for folding, stability and antifungal activity. Sci Rep. 2017 May 16;7(1):1963. doi: 10.1038/s41598-017-02234-w. PubMed PMID: 28512317; PubMed Central PMCID: PMC5434006.

 

  • Garrigues S, Gandía M, Borics A, Marx F, Manzanares P, Marcos JF. Mapping and Identification of Antifungal Peptides in the Putative Antifungal Protein AfpB from the Filamentous Fungus Penicillium digitatum. Front Microbiol. 2017 Apr 6;8:592. doi: 10.3389/fmicb.2017.00592. eCollection 2017. PubMed PMID: 28428776; PubMed Central PMCID: PMC5382200.

 

  • Sonderegger C, Fizil Á, Burtscher L, Hajdu D, Muñoz A, Gáspári Z, Read ND, Batta G, Marx F. D19S Mutation of the Cationic, Cysteine-Rich Protein PAF: Novel Insights into Its Structural Dynamics, Thermal Unfolding and Antifungal Function. PLoS One. 2017 Jan 10;12(1):e0169920. doi: 10.1371/journal.pone.0169920. eCollection 2017. PubMed PMID: 28072824; PubMed Central PMCID: PMC5224997.

 

  • Trixl L, Amort T, Wille A, Zinni M, Ebner S, Hechenberger C, Eichin F, Gabriel H, Schoberleitner I, Huang A, Piatti P, Nat R, Troppmair J, Lusser A. RNA cytosine methyltransferase Nsun3 regulates embryonic stem cell differentiation by promoting mitochondrial activity. Cell Mol Life Sci. 2018 Apr;75(8):1483-1497. doi: 10.1007/s00018-017-2700-0. Epub 2017 Nov 4. PubMed PMID: 29103146; PubMed Central PMCID: PMC5852174.

 

  • Riml C, Amort T, Rieder D, Gasser C, Lusser A, Micura R. Osmium-Mediated Transformation of 4-Thiouridine to Cytidine as Key To Study RNA Dynamics by Sequencing. Angew Chem Int Ed Engl. 2017 Oct 16;56(43):13479-13483. doi: 10.1002/anie.201707465. Epub 2017 Sep 18. PubMed PMID: 28817234.

 

  • Riml C, Lusser A, Ennifar E, Micura R. Synthesis, Thermodynamic Properties, and Crystal Structure of RNA Oligonucleotides Containing 5-Hydroxymethylcytosine. J Org Chem. 2017 Aug 4;82(15):7939-7945. doi: 10.1021/acs.joc.7b01171. Epub 2017 Jul 14. PubMed PMID: 28707898.

 

  • Amort T, Sun X, Khokhlova-Cubberley D, Lusser A. Transcriptome-Wide Detection of 5-Methylcytosine by Bisulfite Sequencing. Methods Mol Biol. 2017;1562:123-142. doi: 10.1007/978-1-4939-6807-7_9. PubMed PMID: 28349458.

 

  • Amort T, Lusser A. Detection of 5-Methylcytosine in Specific Poly(A) RNAs by Bisulfite Sequencing. Methods Mol Biol. 2017;1562:107-121. doi: 10.1007/978-1-4939-6807-7_8. PubMed PMID: 28349457.

 

  • Amort T, Rieder D, Wille A, Khokhlova-Cubberley D, Riml C, Trixl L, Jia XY, Micura R, Lusser A. Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain. Genome Biol. 2017 Jan 5;18(1):1. doi: 10.1186/s13059-016-1139-1. PubMed PMID: 28077169; PubMed Central PMCID: PMC5225599.

 

  • Johns A, Scharf DH, Gsaller F, Schmidt H, Heinekamp T, Straßburger M, Oliver JD, Birch M, Beckmann N, Dobb KS, Gilsenan J, Rash B, Bignell E, Brakhage AA, Bromley MJ. A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity. mBio. 2017 Jul 18;8(4). pii: e01504-16. doi: 10.1128/mBio.01504-16. PubMed PMID: 28720735; PubMed Central PMCID: PMC5516258.

 

  • Misslinger M, Gsaller F, Hortschansky P, Müller C, Bracher F, Bromley MJ, Haas H. The cytochrome b(5) CybE is regulated by iron availability and is crucial for azole resistance in A. fumigatus. Metallomics. 2017 Nov 15;9(11):1655-1665. doi: 10.1039/c7mt00110j. PubMed PMID: 29072765.

 

  • Sass G, Nazik H, Penner J, Shah H, Ansari SR, Clemons KV, Groleau MC, Dietl AM, Visca P, Haas H, Déziel E, Stevens DA. Studies of Pseudomonas aeruginosa Mutants Indicate Pyoverdine as the Central Factor in Inhibition of Aspergillus fumigatus Biofilm. J Bacteriol. 2017 Dec 5;200(1). pii: e00345-17. doi: 10.1128/JB.00345-17. Print 2018 Jan 1. PubMed PMID: 29038255; PubMed Central PMCID: PMC5717155.

 

  • Orasch T, Prattes J, Faserl K, Eigl S, Düttmann W, Lindner H, Haas H, Hoenigl M. Bronchoalveolar lavage triacetylfusarinine C (TAFC) determination for diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies. J Infect. 2017 Oct;75(4):370-373. doi: 10.1016/j.jinf.2017.05.014. Epub 2017 May 31. PubMed PMID: 28576596; PubMed Central PMCID: PMC5757784.

 

  • Summer D, Grossrubatscher L, Petrik M, Michalcikova T, Novy Z, Rangger C, Klingler M, Haas H, Kaeopookum P, von Guggenberg E, Haubner R, Decristoforo C. Developing Targeted Hybrid Imaging Probes by Chelator Scaffolding. Bioconjug Chem. 2017 Jun 21;28(6):1722-1733. doi: 10.1021/acs.bioconjchem.7b00182. Epub 2017 May 10. PubMed PMID: 28462989; PubMed Central PMCID: PMC5481817.

 

  • Nairz M, Schroll A, Haschka D, Dichtl S, Tymoszuk P, Demetz E, Moser P, Haas H, Fang FC, Theurl I, Weiss G. Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection. Front Cell Infect Microbiol. 2017 Apr 11;7:110. doi: 10.3389/fcimb.2017.00110. eCollection 2017. PubMed PMID: 28443246; PubMed Central PMCID: PMC5387078.

 

2016

  • Sonderegger C, Galgóczy L, Garrigues S, Fizil Á, Borics A, Manzanares P, Hegedüs N, Huber A, Marcos JF, Batta G, Marx F. A Penicillium chrysogenum-based expression system for the production of small, cysteine-rich antifungal proteins for structural and functional analyses. Microb Cell Fact. 2016 Nov 11;15(1):192. PubMed PMID: 27835989; PubMed Central PMCID: PMC5106836.

 

  • Ordu O, Lusser A, Dekker NH. Recent insights from in vitro single-molecule studies into nucleosome structure and dynamics. Biophys Rev. 2016;8(Suppl 1):33-49. doi: 10.1007/s12551-016-0212-z. Epub 2016 Oct 18. Review. PubMed PMID: 28058066; PubMed Central PMCID: PMC5167136.

 

  • Wille A, Amort T, Singewald N, Sartori SB, Lusser A. Dysregulation of select ATP-dependent chromatin remodeling factors in high trait anxiety. Behav Brain Res. 2016 Sep 15;311:141-146. doi: 10.1016/j.bbr.2016.05.036. Epub 2016 May 18. PubMed PMID: 27208790.

 

  • Sebald J, Willi M, Schoberleitner I, Krogsdam A, Orth-Höller D, Trajanoski Z, Lusser A. Impact of the Chromatin Remodeling Factor CHD1 on Gut Microbiome Composition of Drosophila melanogaster. PLoS One. 2016 Apr 19;11(4):e0153476. doi: 10.1371/journal.pone.0153476. eCollection 2016. PubMed PMID: 27093431; PubMed Central PMCID: PMC4836739.

 

  • Schafferer S, Khurana R, Refolo V, Venezia S, Sturm E, Piatti P, Hechenberger C, Hackl H, Kessler R, Willi M, Gstir R, Krogsdam A, Lusser A, Poewe W, Wenning GK, Hüttenhofer A, Stefanova N. Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinica Implications. PLoS One. 2016 Mar 10;11(3):e0150705. doi: 10.1371/journal.pone.0150705. eCollection 2016. PubMed PMID: 26962858; PubMed Central PMCID: PMC4786272.

 

  • Bauer I, Varadarajan D, Pidroni A, Gross S, Vergeiner S, Faber B, Hermann M, Tribus M, Brosch G, Graessle S. A Class 1 Histone Deacetylase with Potential as an Antifungal Target. mBio. 2016 Nov 1;7(6). pii: e00831-16. doi: 10.1128/mBio.00831-16. PubMed PMID: 27803184; PubMed Central PMCID: PMC5090035.

 

  • Petrik M, Zhai C, Haas H, Decristoforo C. Siderophores for molecular imaging applications. Clin Transl Imaging. 2017;5(1):15-27. doi: 10.1007/s40336-016-0211-x. Epub 2016 Oct 11. Review. PubMed PMID: 28138436; PubMed Central PMCID: PMC5269471.

 

  • Gsaller F, Hortschansky P, Furukawa T, Carr PD, Rash B, Capilla J, Müller C, Bracher F, Bowyer P, Haas H, Brakhage AA, Bromley MJ. Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex. PLoS Pathog. 2016 Dec 14;12(12):e1006106. doi: 10.1371/journal.ppat.1006106. eCollection 2016 Dec. PubMed PMID: 27973537; PubMed Central PMCID: PMC5156360.

 

  • Hortschansky P, Haas H, Huber EM, Groll M, Brakhage AA. The CCAAT-binding complex (CBC) in Aspergillus species. Biochim Biophys Acta Gene Regul Mech. 2017 May;1860(5):560-570. doi: 10.1016/j.bbagrm.2016.11.008. Epub 2016 Dec 8. Review. PubMed PMID: 27939757.

 

  • Sheridan KJ, Lechner BE, Keeffe GO, Keller MA, Werner ER, Lindner H, Jones GW, Haas H, Doyle S. Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. Sci Rep. 2016 Oct 17;6:35306. doi: 10.1038/srep35306. PubMed PMID: 27748436; PubMed Central PMCID: PMC5066259.

 

  • Pasricha S, Schafferer L, Lindner H, Joanne Boyce K, Haas H, Andrianopoulos A. Differentially regulated high-affinity iron assimilation systems support growth of the various cell types in the dimorphic pathogen Talaromyces marneffei. Mol Microbiol. 2016 Nov;102(4):715-737. doi: 10.1111/mmi.13489. Epub 2016 Sep 23. PubMed PMID: 27558514.

 

  • Gsaller F, Hortschansky P, Furukawa T, Carr PD, Rash B, Capilla J, Müller C, Bracher F, Bowyer P, Haas H, Brakhage AA, Bromley MJ. Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex. PLoS Pathog. 2016 Jul 20;12(7):e1005775. doi: 10.1371/journal.ppat.1005775. eCollection 2016 Jul. Erratum in: PLoS Pathog. 2016 Dec 14;12 (12 ):e1006106. PubMed PMID: 27438727; PubMed Central PMCID: PMC4954732.

 

  • Kaltdorf M, Srivastava M, Gupta SK, Liang C, Binder J, Dietl AM, Meir Z, Haas H, Osherov N, Krappmann S, Dandekar T. Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach. Front Mol Biosci. 2016 Jun 17;3:22. doi: 10.3389/fmolb.2016.00022. eCollection 2016. PubMed PMID: 27379244; PubMed Central PMCID: PMC4911368.

 

  • Zhai C, Franssen GM, Petrik M, Laverman P, Summer D, Rangger C, Haubner R, Haas H, Decristoforo C. Comparison of Ga-68-Labeled Fusarinine C-Based Multivalent RGD Conjugates and [(68)Ga]NODAGA-RGD-In Vivo Imaging Studies in Human Xenograft Tumors. Mol Imaging Biol. 2016 Oct;18(5):758-67. doi: 10.1007/s11307-016-0931-3. PubMed PMID: 26905697; PubMed Central PMCID: PMC5010584.

 

  • Dietl AM, Amich J, Leal S, Beckmann N, Binder U, Beilhack A, Pearlman E, Haas H. Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus. Virulence. 2016 May 18;7(4):465-76. doi: 10.1080/21505594.2016.1146848. Epub 2016 Feb 6. PubMed PMID: 26854126; PubMed Central PMCID: PMC4871644.

 

  • Ben Yaakov D, Rivkin A, Mircus G, Albert N, Dietl AM, Kovalerchick D, Carmeli S, Haas H, Kontoyiannis DP, Osherov N. Identification and characterization of haemofungin, a novel antifungal compound that inhibits the final step of haem biosynthesis. J Antimicrob Chemother. 2016 Apr;71(4):946-52. doi: 10.1093/jac/dkv446. Epub 2016 Jan 7. PubMed PMID: 26747101; PubMed Central PMCID: PMC5757792.

 

  • Petrik M, Zhai C, Novy Z, Urbanek L, Haas H, Decristoforo C. In Vitro and In Vivo Comparison of Selected Ga-68 and Zr-89 Labelled Siderophores. Mol Imaging Biol. 2016 Jun;18(3):344-52. doi: 10.1007/s11307-015-0897-6. PubMed PMID: 26424719; PubMed Central PMCID: PMC4870302.

 

2015

  • Posch B, Irsara C, Gamper FS, Herrmann M, Bindreither D, Fuchs D, Reider N, Redl B, Heufler C. Allergenic Can f 1 and its human homologue Lcn-1 direct dendritic cells to induce divergent immune responses. J Cell Mol Med. 2015 Oct;19(10):2375-84. doi: 10.1111/jcmm.12616. Epub 2015 Jul 27. PubMed PMID: 26218644; PubMed Central PMCID: PMC4594679.

 

  • Virágh M, Marton A, Vizler C, Tóth L, Vágvölgyi C, Marx F, Galgóczy L. Insight into the antifungal mechanism of Neosartorya fischeri antifungal protein. Protein Cell. 2015 Jul;6(7):518-28. doi: 10.1007/s13238-015-0167-z. Epub 2015 May 22. PubMed PMID: 25994413; PubMed Central PMCID: PMC4491047.

 

  • Binder U, Benčina M, Fizil Á, Batta G, Chhillar AK, Marx F. Protein kinase A signaling and calcium ions are major players in PAF mediated toxicity against Aspergillus niger. FEBS Lett. 2015 May 8;589(11):1266-71. doi: 10.1016/j.febslet.2015.03.037. Epub 2015 Apr 14. PubMed PMID: 25882631; PubMed Central PMCID: PMC4424949.

 

  • Fizil Á, Gáspári Z, Barna T, Marx F, Batta G. "Invisible" conformers of an antifungal disulfide protein revealed by constrained cold and heat unfolding, CEST-NMR experiments, and molecular dynamics calculations. Chemistry. 2015 Mar 23;21(13):5136-44. doi: 10.1002/chem.201404879. Epub 2015 Feb 12. PubMed PMID: 25676351; PubMed Central PMCID: PMC4464532.

 

  • Wille A, Maurer V, Piatti P, Whittle N, Rieder D, Singewald N, Lusser A. Impaired Contextual Fear Extinction Learning is Associated with Aberrant Regulation of CHD-Type Chromatin Remodeling Factors. Front Behav Neurosci. 2015 Nov 18;9:313. doi: 10.3389/fnbeh.2015.00313. eCollection 2015. PubMed PMID: 26635563; PubMed Central PMCID: PMC4649039.

 

  • Boltengagen M, Huang A, Boltengagen A, Trixl L, Lindner H, Kremser L, Offterdinger M, Lusser A. A novel role for the histone acetyltransferase Hat1 in the CENP-A/CID assembly pathway in Drosophila melanogaster. Nucleic Acids Res. 2016 Mar 18;44(5):2145-59. doi: 10.1093/nar/gkv1235. Epub 2015 Nov 19. PubMed PMID: 26586808; PubMed Central PMCID: PMC4797270.

 

  • Rieder D, Amort T, Kugler E, Lusser A, Trajanoski Z. meRanTK: methylated RNA analysis ToolKit. Bioinformatics. 2016 Mar 1;32(5):782-5. doi: 1093/bioinformatics/btv647. Epub 2015 Nov 4. PubMed PMID: 26543174.

 

  • Vlijm R, Lee M, Ordu O, Boltengagen A, Lusser A, Dekker NH, Dekker C. Comparing the Assembly and Handedness Dynamics of (H3.3-H4)2 Tetrasomes to Canonical Tetrasomes. PLoS One. 2015 Oct 27;10(10):e0141267. doi: 10.1371/journal.pone.0141267. eCollection 2015. PubMed PMID: 26506534; PubMed Central PMCID: PMC4623960.

 

  • Piatti P, Lim CY, Nat R, Villunger A, Geley S, Shue YT, Soratroi C, Moser M, Lusser A. Embryonic stem cell differentiation requires full length Chd1. Sci Rep. 2015 Jan 26;5:8007. doi: 10.1038/srep08007. PubMed PMID: 25620209; PubMed Central PMCID: PMC4306112.

 

  • Vlijm R, Lee M, Lipfert J, Lusser A, Dekker C, Dekker NH. Nucleosome assembly dynamics involve spontaneous fluctuations in the handedness of tetrasomes. Cell Rep. 2015 Jan 13;10(2):216-25. doi: 10.1016/j.celrep.2014.12.022. Epub 2015 Jan 8. PubMed PMID: 25578730.

 

  • Wang L, Kofler M, Brosch G, Melesina J, Sippl W, Martinez ED, Easmon J. 2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity. PLoS 2015 Dec 23;10(12):e0134556. doi: 10.1371/journal.pone.0134556. eCollection 2015. PubMed PMID: 26698121; PubMed Central PMCID: PMC4689404.

 

  • Schafferer L, Beckmann N, Binder U, Brosch G, Haas H. AmcA-a putative mitochondrial ornithine transporter supporting fungal siderophore biosynthesis. Front Microbiol. 2015 Apr 7;6:252. doi: 10.3389/fmicb.2015.00252. eCollection 2015. PubMed PMID: 25904899; PubMed Central PMCID: PMC4387927.

 

  • Haas H. How to trigger a fungal weapon. Elife. 2015 Sep 1;4. doi: 10.7554/eLife.10504. PubMed PMID: 26327696; PubMed Central PMCID: PMC4555636.

 

  • Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM. Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis. PLoS Pathog. 2015 Jun 18;11(6):e1004943. doi: 10.1371/journal.ppat.1004943. eCollection 2015 Jun. PubMed PMID: 26086393; PubMed Central PMCID: PMC4472839.

 

  • Zhai C, Summer D, Rangger C, Franssen GM, Laverman P, Haas H, Petrik M, Haubner R, Decristoforo C. Novel Bifunctional Cyclic Chelator for (89)Zr Labeling-Radiolabeling and Targeting Properties of RGD Conjugates. Mol Pharm. 2015 Jun 1;12(6):2142-50. doi: 10.1021/acs.molpharmaceut.5b00128. Epub 2015 May 19. PubMed PMID: 25941834; PubMed Central PMCID: PMC4453016.

 

  • Schafferer L, Beckmann N, Binder U, Brosch G, Haas H. AmcA-a putative mitochondrial ornithine transporter supporting fungal siderophore biosynthesis. Front Microbiol. 2015 Apr 7;6:252. doi: 10.3389/fmicb.2015.00252. eCollection 2015. PubMed PMID: 25904899; PubMed Central PMCID: PMC4387927.

 

  • Zhai C, Summer D, Rangger C, Haas H, Haubner R, Decristoforo C. Fusarinine C, a novel siderophore-based bifunctional chelator for radiolabeling with Gallium-68. J Labelled Comp Radiopharm. 2015 May 15;58(5):209-14. doi: 10.1002/jlcr.3286. Epub 2015 Apr 15. PubMed PMID: 25874571; PubMed Central PMCID:

 

  • Baldin C, Valiante V, Krüger T, Schafferer L, Haas H, Kniemeyer O, Brakhage AA. Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation. Proteomics. 2015 Jul;15(13):2230-43. doi: 10.1002/pmic.201400584. Epub 2015 May 26. PubMed PMID: 25728394.

 

  • Briard B, Bomme P, Lechner BE, Mislin GL, Lair V, Prévost MC, Latgé JP, Haas H, Beauvais A. Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines. Sci Rep. 2015 Feb 10;5:8220. doi: 10.1038/srep08220. PubMed PMID: 25665925; PubMed Central PMCID: PMC5389140.

 

  • Haas H, Petrik M, Decristoforo C. An iron-mimicking, Trojan horse-entering fungi--has the time come for molecular imaging of fungal infections? PLoS Pathog. 2015 Jan 29;11(1):e1004568. doi: 10.1371/journal.ppat.1004568. eCollection 2015 Jan. PubMed PMID: 25634225; PubMed Central PMCID: PMC4310729.

 

  • Hortschansky P, Ando E, Tuppatsch K, Arikawa H, Kobayashi T, Kato M, Haas H, Brakhage AA. Deciphering the combinatorial DNA-binding code of the CCAAT-binding complex and the iron-regulatory basic region leucine zipper (bZIP) transcription factor HapX. J Biol Chem. 2015 Mar 6;290(10):6058-70. doi: 10.1074/jbc.M114.628677. Epub 2015 Jan 14. PubMed PMID: 25589790; PubMed Central PMCID: PMC4358248.

 

  • Knetsch PA, Zhai C, Rangger C, Blatzer M, Haas H, Kaeopookum P, Haubner R, Decristoforo C. [(68)Ga]FSC-(RGD)3 a trimeric RGD peptide for imaging αvβ3 integrin expression based on a novel siderophore derived chelating scaffold-synthesis and evaluation. Nucl Med Biol. 2015 Feb;42(2):115-22. doi: 10.1016/j.nucmedbio.2014.10.001. Epub 2014 Oct 13. PubMed PMID: 25459110; PubMed Central PMCID: PMC4289911.

 

2014

  • Staudinger T, Redl B, Glasgow BJ. Antibacterial activity of rifamycins for M. smegmatis with comparison of oxidation and binding to tear lipocalin. Biochim Biophys Acta. 2014 Apr;1844(4):750-8. doi: 10.1016/j.bbapap.2014.02.001. Epub 2014 Feb 12. PubMed PMID: 24530503; PubMed Central PMCID: PMC3992280.

 

  • Katan AJ, Vlijm R, Lusser A, Dekker C. Dynamics of nucleosomal structures measured by high-speed atomic force microscopy. Small. 2015 Feb 25;11(8):976-84. doi: 10.1002/smll.201401318. Epub 2014 Oct 21. PubMed PMID: 25336288.

 

  • Etemad S, Obermair GJ, Bindreither D, Benedetti A, Stanika R, Di Biase V, Burtscher V, Koschak A, Kofler R, Geley S, Wille A, Lusser A, Flockerzi V, Flucher BE. Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression. J Neurosci. 2014 Jan 22;34(4):1446-61. doi: 10.1523/JNEUROSCI.3935-13.2014. PubMed PMID: 24453333; PubMed Central PMCID: PMC3898300.

 

  • Valente S, Trisciuoglio D, De Luca T, Nebbioso A, Labella D, Lenoci A, Bigogno C, Dondio G, Miceli M, Brosch G, Del Bufalo D, Altucci L, Mai A. 1,3,4-Oxadiazole-containing histone deacetylase inhibitors: anticancer activities in cancer cells. J Med Chem. 2014 Jul 24;57(14):6259-65. doi: 10.1021/jm500303u. Epub 2014 Jul 8. PubMed PMID: 24972008.

 

  • Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, Zezula J, Weissmann S, Xie Y, Schöfer C, Schlederer M, Brosch G, Matthias P, Selfridge J, Lassmann H, Knoblich JA, Seiser C. A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development. 2014 Feb;141(3):604-616. doi: 10.1242/dev.100487. PubMed PMID: 24449838; PubMed Central PMCID: PMC4773893.

 

  • Wiemann P, Lechner BE, Baccile JA, Velk TA, Yin WB, Bok JW, Pakala S, Losada L, Nierman WC, Schroeder FC, Haas H, Keller NP. Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Front Microbiol. 2014 Oct 24;5:530. doi: 10.3389/fmicb.2014.00530. eCollection 2014. PubMed PMID: 25386169; PubMed Central PMCID: PMC4208449.

 

  • Chung D, Barker BM, Carey CC, Merriman B, Werner ER, Lechner BE, Dhingra S, Cheng C, Xu W, Blosser SJ, Morohashi K, Mazurie A, Mitchell TK, Haas H, Mitchell AP, Cramer RA. ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence. PLoS Pathog. 2014 Nov 6;10(11):e1004487. doi: 10.1371/journal.ppat.1004487. eCollection 2014 Nov. Erratum in: PLoS Pathog. 2014 Nov;10(11):e1004576. PubMed PMID: 25375670; PubMed Central PMCID: PMC4223079.

 

  • Petrik M, Vlckova A, Novy Z, Urbanek L, Haas H, Decristoforo C. Selected ⁶⁸Ga-siderophores versus ⁶⁸Ga-colloid and ⁶⁸Ga-citrate: biodistribution and small animal imaging in mice. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Mar;159(1):60-6. doi: 10.5507/bp.2014.052. Epub 2014 Oct 29. PubMed PMID: 25363728; PubMed Central PMCID: PMC4843960.

 

  • Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM. The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis. PLoS Pathog. 2014 Oct 16;10(10):e1004413. doi: 10.1371/journal.ppat.1004413. eCollection 2014 Oct. Erratum in: PLoS Pathog. 2015 Apr;11(4):e1004802. PLoS Pathog. 2015 Jun 18;11(6):e1004943. PubMed PMID: 25329394; PubMed Central PMCID: PMC4199764.

 

  • Silva-Bailão MG, Bailão EF, Lechner BE, Gauthier GM, Lindner H, Bailão AM, Haas H, de Almeida Soares CM. Hydroxamate production as a high affinity iron acquisition mechanism in Paracoccidioides spp. PLoS One. 2014 Aug 26;9(8):e105805. doi: 10.1371/journal.pone.0105805. eCollection 2014. PubMed PMID: 25157575; PubMed Central PMCID: PMC4144954.

 

  • Haas H. Fungal siderophore metabolism with a focus on Aspergillus fumigatus. Nat Prod Rep. 2014 Oct;31(10):1266-76. doi: 10.1039/c4np00071d. Review. PubMed PMID: 25140791; PubMed Central PMCID: PMC4162504.

 

  • Gsaller F, Hortschansky P, Beattie SR, Klammer V, Tuppatsch K, Lechner BE, Rietzschel N, Werner ER, Vogan AA, Chung D, Mühlenhoff U, Kato M, Cramer RA, Brakhage AA, Haas H. The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess. EMBO J. 2014 Oct 1;33(19):2261-76. doi: 10.15252/embj.201489468. Epub 2014 Aug 4. PubMed PMID: 25092765; PubMed Central PMCID: PMC4232046.

 

  • Franken AC, Lechner BE, Werner ER, Haas H, Lokman BC, Ram AF, van den Hondel CA, de Weert S, Punt PJ. Genome mining and functional genomics for siderophore production in Aspergillus niger. Brief Funct Genomics. 2014 Nov;13(6):482-92. doi: 10.1093/bfgp/elu026. Epub 2014 Jul 25. PubMed PMID: 25062661.

 

  • Hillmann F, Linde J, Beckmann N, Cyrulies M, Strassburger M, Heinekamp T, Haas H, Guthke R, Kniemeyer O, Brakhage AA. The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus. Mol Microbiol. 2014 Aug;93(3):539-53. doi: 10.1111/mmi.12679. Epub 2014 Jul 7. PubMed PMID: 24948085.

 

  • Vergeiner S, Schafferer L, Haas H, Müller T. Improved MALDI-TOF microbial mass spectrometry imaging by application of a dispersed solid matrix. J Am Soc Mass Spectrom. 2014 Aug;25(8):1498-501. doi: 10.1007/s13361-014-0923-y. Epub 2014 Jun 4. PubMed PMID: 24894842.

 

  • Albarouki E, Schafferer L, Ye F, von Wirén N, Haas H, Deising HB. Biotrophy-specific downregulation of siderophore biosynthesis in Colletotrichum graminicola is required for modulation of immune responses of maize. Mol 2014 Apr;92(2):338-55. doi: 10.1111/mmi.12561. Epub 2014 Mar 17. PubMed PMID: 24674132; PubMed Central PMCID: PMC4235341.

 

  • Blatzer M, Gsaller F, Abt B, Schrettl M, Specht T, Haas H. An endogenous promoter for conditional gene expression in Acremonium chrysogenum: the xylan and xylose inducible promoter xyl1(P.). J Biotechnol. 2014 Jan;169:82-6. doi: 10.1016/j.jbiotec.2013.11.003. Epub 2013 Nov 15. PubMed PMID: 24246269.

 

  • Petrik M, Haas H, Laverman P, Schrettl M, Franssen GM, Blatzer M, Decristoforo C. 68Ga-triacetylfusarinine C and 68Ga-ferrioxamine E for Aspergillus infection imaging: uptake specificity in various microorganisms. Mol Imaging Biol. 2014 Feb;16(1):102-8. doi: 10.1007/s11307-013-0654-7. PubMed PMID: 23818006; PubMed Central PMCID: PMC3823598.

 

2013

  • Hegedüs N, Marx F. Antifungal proteins: More than antimicrobials? Fungal Biol Rev. 2013 Jan;26(4):132-145. PubMed PMID: 23412850; PubMed Central PMCID: PMC3569713.

 

  • Amort T, Soulière MF, Wille A, Jia XY, Fiegl H, Wörle H, Micura R, Lusser A. Long non-coding RNAs as targets for cytosine methylation. RNA Biol. 2013 Jun;10(6):1003-8. doi: 10.4161/rna.24454. Epub 2013 Apr 1. PubMed PMID: 23595112; PubMed Central PMCID: PMC4111728.

 

  • Winter M, Moser MA, Meunier D, Fischer C, Machat G, Mattes K, Lichtenberger BM, Brunmeir R, Weissmann S, Murko C, Humer C, Meischel T, Brosch G, Matthias P, Sibilia M, Seiser C. Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis. EMBO J. 2013 Dec 11;32(24):3176-91. doi: 10.1038/emboj.2013.243. Epub 2013 Nov 15. PubMed PMID: 24240174; PubMed Central PMCID: PMC3981143.

 

  • Franken AC, Werner ER, Haas H, Lokman BC, van den Hondel CA, Ram AF, de Weert S, Punt PJ. The role of coproporphyrinogen III oxidase and ferrochelatase genes in heme biosynthesis and regulation in Aspergillus niger. Appl Microbiol 2013 Nov;97(22):9773-85. doi: 10.1007/s00253-013-5274-2. Epub 2013 Oct 11. PubMed PMID: 24113826.

 

  • Haselwandter K, Häninger G, Ganzera M, Haas H, Nicholson G, Winkelmann G. Linear fusigen as the major hydroxamate siderophore of the ectomycorrhizal Basidiomycota Laccaria laccata and Laccaria bicolor. Biometals. 2013 Dec;26(6):969-79. doi: 10.1007/s10534-013-9673-8. Epub 2013 Sep 22. PubMed PMID: 24057327.

 

  • Gründlinger M, Gsaller F, Schrettl M, Lindner H, Haas H. Aspergillus fumigatus SidJ mediates intracellular siderophore hydrolysis. Appl Environ Microbiol. 2013 Dec;79(23):7534-6. doi: 10.1128/AEM.01285-13. Epub 2013 Sep 13. PubMed PMID: 24038704; PubMed Central PMCID: PMC3837724.

 

  • Amich J, Schafferer L, Haas H, Krappmann S. Regulation of Sulphur assimilation is essential for virulence and affects iron homeostasis of the human-pathogenic mould Aspergillus fumigatus. PLoS Pathog. 2013;9(8):e1003573. doi: 10.1371/journal.ppat.1003573. Epub 2013 Aug 29. PubMed PMID: 24009505; PubMed Central PMCID: PMC3757043.

 

  • Steinchen W, Lackner G, Yasmin S, Schrettl M, Dahse HM, Haas H, Hoffmeister D. Bimodular peptide synthetase SidE produces fumarylalanine in the human pathogen Aspergillus fumigatus. Appl Environ Microbiol. 2013 Nov;79(21):6670-6. doi: 10.1128/AEM.02642-13. Epub 2013 Aug 23. PubMed PMID: 23974138; PubMed Central PMCID: PMC3811484.

 

  • Leal SM Jr, Roy S, Vareechon C, Carrion Sd, Clark H, Lopez-Berges MS, Di Pietro A, Schrettl M, Beckmann N, Redl B, Haas H, Pearlman E. Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum. PLoS Pathog. 2013;9(7):e1003436. doi: 1371/journal.ppat.1003436. Epub 2013 Jul 11. Erratum in: PLoS Pathog. 2013 Jul;9(7). doi:10.1371/annotation/4f388450-90fe-4c65-9b9b-71a2b7935ac0. diPietro, Antonio [corrected to Di Pietro, Antonio]. PubMed PMID: 23853581; PubMed Central PMCID: PMC3708856.

 

  • Beckmann N, Schafferer L, Schrettl M, Binder U, Talasz H, Lindner H, Haas H. Characterization of the Link between Ornithine, Arginine, Polyamine and Siderophore Metabolism in Aspergillus fumigatus. PLoS One. 2013 Jun 18;8(6):e67426. doi: 10.1371/journal.pone.0067426. Print 2013. PubMed PMID: 23825660; PubMed Central PMCID: PMC3688985.

 

  • Gründlinger M, Yasmin S, Lechner BE, Geley S, Schrettl M, Hynes M, Haas H. Fungal siderophore biosynthesis is partially localized in peroxisomes. Mol 2013 Jun;88(5):862-75. doi: 10.1111/mmi.12225. Epub 2013 Apr 26. PubMed PMID: 23617799; PubMed Central PMCID: PMC3709128.

 

  • López-Berges MS, Turrà D, Capilla J, Schafferer L, Matthijs S, Jöchl C, Cornelis P, Guarro J, Haas H, Di Pietro A. Iron competition in fungus-plant interactions: the battle takes place in the rhizosphere. Plant Signal Behav. 2013 Feb;8(2):e23012. doi: 10.4161/psb.23012. Epub 2013 Jan 8. PubMed PMID: 23299422; PubMed Central PMCID: PMC3656999.

 

2012

  • Vlijm R, Smitshuijzen JS, Lusser A, Dekker C. NAP1-assisted nucleosome assembly on DNA measured in real time by single-molecule magnetic tweezers. PLoS One. 2012;7(9):e46306. doi: 10.1371/journal.pone.0046306. Epub 2012 Sep 25. PubMed PMID: 23050009; PubMed Central PMCID: PMC3457989.

 

  • Sebald J, Morettini S, Podhraski V, Lass-Flörl C, Lusser A. CHD1 contributes to intestinal resistance against infection by P. aeruginosa in Drosophila melanogaster. PLoS One. 2012;7(8):e43144. doi: 10.1371/journal.pone.0043144. Epub 2012 Aug 13. PubMed PMID: 22912810; PubMed Central PMCID: PMC3418260.

 

  • Fischnaller S, Dowell FE, Lusser A, Schlick-Steiner BC, Steiner FM. Non-destructive species identification of Drosophila obscura and D. subobscura (Diptera) using near-infrared spectroscopy. Fly (Austin). 2012 Oct-Dec;6(4):284-9. doi: 10.4161/fly.21535. Epub 2012 Aug 13. PubMed PMID: 22885252; PubMed Central PMCID: PMC3519663.

 

  • Saeed M, Schwarze F, Loidl A, Meraner J, Lechner M, Loidl P. In vitro phosphorylation and acetylation of the murine pocket protein Rb2/p130. PLoS One. 2012;7(9):e46174. doi: 10.1371/journal.pone.0046174. Epub 2012 Sep 24. PubMed PMID: 23029429; PubMed Central PMCID: PMC3454344.

 

  • Gsaller F, Eisendle M, Lechner BE, Schrettl M, Lindner H, Müller D, Geley S, Haas H. The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus. Metallomics. 2012 Dec;4(12):1262-70. doi: 10.1039/c2mt20179h. Epub 2012 Nov 14. PubMed PMID: 23151814.

 

  • Chung D, Haas H, Cramer RA. Coordination of hypoxia adaptation and iron homeostasis in human pathogenic fungi. Front Microbiol. 2012 Nov 6;3:381. doi: 10.3389/fmicb.2012.00381. eCollection 2012. PubMed PMID: 23133438; PubMed Central PMCID: PMC3490150.

 

  • Gsaller F, Blatzer M, Abt B, Schrettl M, Lindner H, Haas H. The first promoter for conditional gene expression in Acremonium chrysogenum: iron starvation-inducible mir1(P). J Biotechnol. 2013 Jan 10;163(1):77-80. doi: 10.1016/j.jbiotec.2012.10.008. Epub 2012 Oct 23. PubMed PMID: 23089729.

 

  • López-Berges MS, Capilla J, Turrà D, Schafferer L, Matthijs S, Jöchl C, Cornelis P, Guarro J, Haas H, Di Pietro A. HapX-mediated iron homeostasis is essential for rhizosphere competence and virulence of the soilborne pathogen Fusarium oxysporum. Plant Cell. 2012 Sep;24(9):3805-22. doi: 10.1105/tpc.112.098624. Epub 2012 Sep 11. PubMed PMID: 22968717; PubMed Central PMCID: PMC3480304.

 

  • Petrik M, Franssen GM, Haas H, Laverman P, Hörtnagl C, Schrettl M, Helbok A, Lass-Flörl C, Decristoforo C. Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging. Eur J Nucl Med Mol Imaging. 2012 Jul;39(7):1175-83. doi: 10.1007/s00259-012-2110-3. Epub 2012 Apr 24. PubMed PMID: 22526953; PubMed Central PMCID: PMC3369139.

 

  • Haas H. Iron - A Key Nexus in the Virulence of Aspergillus fumigatus. Front Microbiol. 2012 Feb 6;3:28. doi: 10.3389/fmicb.2012.00028. eCollection 2012. PubMed PMID: 22347220; PubMed Central PMCID: PMC3272694.

 

  • Linde J, Hortschansky P, Fazius E, Brakhage AA, Guthke R, Haas H. Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach. BMC Syst Biol. 2012 Jan 19;6:6. doi: 10.1186/1752-0509-6-6. PubMed PMID: 22260221; PubMed Central PMCID: PMC3305660.

 

  • Petrik M, Haas H, Schrettl M, Helbok A, Blatzer M, Decristoforo C. In vitro and in vivo evaluation of selected 68Ga-siderophores for infection imaging. Nucl Med Biol. 2012 Apr;39(3):361-9. doi: 10.1016/j.nucmedbio.2011.09.012. Epub 2011 Dec 14. PubMed PMID: 22172389; PubMed Central PMCID: PMC3314960.

 

2011

  • Eigentler A, Pócsi I, Marx F. The anisin1 gene encodes a defensin-like protein and supports the fitness of Aspergillus nidulans. Arch Microbiol. 2012 Jun;194(6):427-37. doi: 10.1007/s00203-011-0773-y. Epub 2011 Nov 24. PubMed PMID: 22113351; PubMed Central PMCID: PMC3354322.

 

  • Binder U, Bencina M, Eigentler A, Meyer V, Marx F. The Aspergillus giganteus antifungal protein AFPNN5353 activates the cell wall integrity pathway and perturbs calcium homeostasis. BMC Microbiol. 2011 Sep 23;11:209. doi: 10.1186/1471-2180-11-209. PubMed PMID: 21943024; PubMed Central PMCID: PMC3197501.

 

  • Hegedüs N, Sigl C, Zadra I, Pócsi I, Marx F. The paf gene product modulates asexual development in Penicillium chrysogenum. J Basic Microbiol. 2011 Jun;51(3):253-62. doi: 10.1002/jobm.201000321. Epub 2011 Feb 7. PubMed PMID: 21298690; PubMed Central PMCID: PMC3103751.

 

  • Piatti P, Zeilner A, Lusser A. ATP-dependent chromatin remodeling factors and their roles in affecting nucleosome fiber composition. Int J Mol Sci. 2011;12(10):6544-65. doi: 10.3390/ijms12106544. Epub 2011 Oct 6. Review. PubMed PMID: 22072904; PubMed Central PMCID: PMC3210995.

 

  • Valente S, Tardugno M, Conte M, Cirilli R, Perrone A, Ragno R, Simeoni S, Tramontano A, Massa S, Nebbioso A, Miceli M, Franci G, Brosch G, Altucci L, Mai A. Novel cinnamyl hydroxyamides and 2-aminoanilides as histone deacetylase inhibitors: apoptotic induction and cytodifferentiation activity. ChemMedChem. 2011 Apr 4;6(4):698-712. doi: 10.1002/cmdc.201000535. Epub 2011 Mar 4. PubMed PMID: 21374822.

 

  • Blatzer M, Barker BM, Willger SD, Beckmann N, Blosser SJ, Cornish EJ, Mazurie A, Grahl N, Haas H, Cramer RA. SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus. PLoS Genet. 2011 Dec;7(12):e1002374. doi: 1371/journal.pgen.1002374. Epub 2011 Dec 1. PubMed PMID: 22144905; PubMed Central PMCID: PMC3228822.

 

  • Yasmin S, Alcazar-Fuoli L, Gründlinger M, Puempel T, Cairns T, Blatzer M, Lopez JF, Grimalt JO, Bignell E, Haas H. Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):E497-504. doi: 10.1073/pnas.1106399108. Epub 2011 Nov 21. PubMed PMID: 22106303; PubMed Central PMCID: PMC3286978.

 

  • Jain R, Valiante V, Remme N, Docimo T, Heinekamp T, Hertweck C, Gershenzon J, Haas H, Brakhage AA. The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus. Mol Microbiol. 2011 Oct;82(1):39-53. doi: 10.1111/j.1365-2958.2011.07778.x. Epub 2011 Aug 30. PubMed PMID: 21883519; PubMed Central PMCID: PMC3229709.

 

  • Blatzer M, Binder U, Haas H. The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation. Fungal Genet Biol. 2011 Nov;48(11):1027-33. doi: 10.1016/j.fgb.2011.07.009. Epub 2011 Aug 5. PubMed PMID: 21840411; PubMed Central PMCID: PMC3188701.

 

  • Hegedus N, Leiter E, Kovács B, Tomori V, Kwon NJ, Emri T, Marx F, Batta G, Csernoch L, Haas H, Yu JH, Pócsi I. The small molecular mass antifungal protein of Penicillium chrysogenum--a mechanism of action oriented review. J Basic Microbiol. 2011 Dec;51(6):561-71. doi: 10.1002/jobm.201100041. Epub 2011 Jul 21. Review. PubMed PMID: 21780144.

 

  • Schrettl M, Haas H. Iron homeostasis--Achilles' heel of Aspergillus fumigatus? Curr Opin Microbiol. 2011 Aug;14(4):400-5. doi: 10.1016/j.mib.2011.06.002. Epub 2011 Jul 1. Review. PubMed PMID: 21724450; PubMed Central PMCID: PMC3162135.

 

  • Blatzer M, Schrettl M, Sarg B, Lindner HH, Pfaller K, Haas H. SidL, an Aspergillus fumigatus transacetylase involved in biosynthesis of the siderophores ferricrocin and hydroxyferricrocin. Appl Environ Microbiol. 2011 Jul;77(14):4959-66. doi: 10.1128/AEM.00182-11. Epub 2011 May 27. PubMed PMID: 21622789; PubMed Central PMCID: PMC3147410.

 

  • Vödisch M, Scherlach K, Winkler R, Hertweck C, Braun HP, Roth M, Haas H, Werner ER, Brakhage AA, Kniemeyer O. Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. J Proteome Res. 2011 May 6;10(5):2508-24. doi: 10.1021/pr1012812. Epub 2011 Mar 29. PubMed PMID: 21388144; PubMed Central PMCID: PMC3091480.

 

2010

  • Sigl C, Haas H, Specht T, Pfaller K, Kürnsteiner H, Zadra I. Among developmental regulators, StuA but not BrlA is essential for penicillin V production in Penicillium chrysogenum. Appl Environ Microbiol. 2011 Feb;77(3):972-82. doi: 10.1128/AEM.01557-10. Epub 2010 Dec 10. PubMed PMID: 21148688; PubMed Central PMCID: PMC3028705. 2010

 

  • Binder U, Chu M, Read ND, Marx F. The antifungal activity of the Penicillium chrysogenum protein PAF disrupts calcium homeostasis in Neurospora crassa. Eukaryot Cell. 2010 Sep;9(9):1374-82. doi: 10.1128/EC.00050-10. Epub 2010 Jul 9. PubMed PMID: 20622001; PubMed Central PMCID: PMC2937333.

 

  • Binder U, Oberparleiter C, Meyer V, Marx F. The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans. Mol Microbiol. 2010 Jan;75(2):294-307. doi: 10.1111/j.1365-2958.2009.06936.x. Epub 2009 Nov 2. PubMed PMID: 19889092; PubMed Central PMCID: PMC2814085.

 

  • Morettini S, Tribus M, Zeilner A, Sebald J, Campo-Fernandez B, Scheran G, Wörle H, Podhraski V, Fyodorov DV, Lusser A. The chromodomains of CHD1 are critical for enzymatic activity but less important for chromatin localization. Nucleic Acids Res. 2011 Apr;39(8):3103-15. doi: 10.1093/nar/gkq1298. Epub 2010 Dec 21. PubMed PMID: 21177652; PubMed Central PMCID: PMC3082874.

 

  • Podhraski V, Campo-Fernandez B, Wörle H, Piatti P, Niederegger H, Böck G, Fyodorov DV, Lusser A. CenH3/CID incorporation is not dependent on the chromatin assembly factor CHD1 in Drosophila. PLoS One. 2010 Apr 9;5(4):e10120. doi: 10.1371/journal.pone.0010120. PubMed PMID: 20396651; PubMed Central PMCID: PMC2852906.

 

  • Bauer I, Graessle S, Loidl P, Hohenstein K, Brosch G. Novel insights into the functional role of three protein arginine methyltransferases in Aspergillus nidulans. Fungal Genet Biol. 2010 Jun;47(6):551-61. doi: 10.1016/j.fgb.2010.03.006. Epub 2010 Mar 23. PubMed PMID: 20338257.

 

  • Castellano S, Milite C, Ragno R, Simeoni S, Mai A, Limongelli V, Novellino E, Bauer I, Brosch G, Spannhoff A, Cheng D, Bedford MT, Sbardella G. Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1). ChemMedChem. 2010 Mar 1;5(3):398-414. doi: 10.1002/cmdc.200900459. PubMed PMID: 20091730.

 

  • Schrettl M, Beckmann N, Varga J, Heinekamp T, Jacobsen ID, Jöchl C, Moussa TA, Wang S, Gsaller F, Blatzer M, Werner ER, Niermann WC, Brakhage AA, Haas H. HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus. PLoS Pathog. 2010 Sep 30;6(9):e1001124. doi: 10.1371/journal.ppat.1001124. PubMed PMID: 20941352; PubMed Central PMCID: PMC2947994.

 

  • Schrettl M, Ibrahim-Granet O, Droin S, Huerre M, Latgé JP, Haas H. The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages. Microbes Infect. 2010 Nov;12(12-13):1035-41. doi: 10.1016/j.micinf.2010.07.005. Epub 2010 Jul 24. PubMed PMID: 20659583; PubMed Central PMCID: PMC2977081.

 

  • Schrettl M, Carberry S, Kavanagh K, Haas H, Jones GW, O'Brien J, Nolan A, Stephens J, Fenelon O, Doyle S. Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin. PLoS Pathog. 2010 Jun 10;6(6):e1000952. doi: 10.1371/journal.ppat.1000952. PubMed PMID: 20548963; PubMed Central PMCID: PMC2883607.

 

  • Chamilos G, Bignell EM, Schrettl M, Lewis RE, Leventakos K, May GS, Haas H, Kontoyiannis DP. Exploring the concordance of Aspergillus fumigatus pathogenicity in mice and Toll-deficient flies. Med Mycol. 2010 May;48(3):506-10. doi: 10.3109/13693780903225813. PubMed PMID: 20370364.

 

  • Petrik M, Haas H, Dobrozemsky G, Lass-Flörl C, Helbok A, Blatzer M, Dietrich H, Decristoforo C. 68Ga-siderophores for PET imaging of invasive pulmonary aspergillosis: proof of principle. J Nucl Med. 2010 Apr;51(4):639-45. doi: 10.2967/jnumed.109.072462. PubMed PMID: 20351354; PubMed Central PMCID: PMC2992174.

 

  • Thön M, Al Abdallah Q, Hortschansky P, Scharf DH, Eisendle M, Haas H, Brakhage AA. The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes. Nucleic Acids Res. 2010 Mar;38(4):1098-113. doi: 1093/nar/gkp1091. Epub 2009 Dec 3. PubMed PMID: 19965775; PubMed Central PMCID: PMC2831313.

 

  • Tribus M, Bauer I, Galehr J, Rieser G, Trojer P, Brosch G, Loidl P, Haas H, Graessle S. A novel motif in fungal class 1 histone deacetylases is essential for growth and development of Aspergillus. Mol Biol Cell. 2010 Jan 15;21(2):345-53. doi: 10.1091/mbc.E09-08-0750. Epub 2009 Nov 25. PubMed PMID: 19940017; PubMed Central PMCID: PMC2808227.

 

2009

  • Batta G, Barna T, Gáspári Z, Sándor S, Kövér KE, Binder U, Sarg B, Kaiserer L, Chhillar AK, Eigentler A, Leiter E, Hegedüs N, Pócsi I, Lindner H, Marx F. Functional aspects of the solution structure and dynamics of PAF--a highly-stable antifungal protein from Penicillium chrysogenum. FEBS J. 2009 May;276(10):2875-90. doi: 10.1111/j.1742-4658.2009.07011.x. PubMed PMID: 19459942; PubMed Central PMCID: PMC4290664.

 

  • Tribus M, Bauer I, Galehr J, Rieser G, Trojer P, Brosch G, Loidl P, Haas H, Graessle S. A novel motif in fungal class 1 histone deacetylases is essential for growth and development of Aspergillus. Mol Biol Cell. 2010 Jan 15;21(2):345-53. doi: 10.1091/mbc.E09-08-0750. Epub 2009 Nov 25. PubMed PMID: 19940017; PubMed Central PMCID: PMC2808227.

 

  • Yasmin S, Abt B, Schrettl M, Moussa TA, Werner ER, Haas H. The interplay between iron and zinc metabolism in Aspergillus fumigatus. Fungal Genet Biol. 2009 Sep;46(9):707-13. doi: 10.1016/j.fgb.2009.05.003. Epub 2009 May 19. PubMed PMID: 19460452.

 

  • Wallner A, Blatzer M, Schrettl M, Sarg B, Lindner H, Haas H. Ferricrocin, a siderophore involved in intra- and transcellular iron distribution in Aspergillus fumigatus. Appl Environ Microbiol. 2009 Jun;75(12):4194-6. doi: 10.1128/AEM.00479-09. Epub 2009 Apr 17. PubMed PMID: 19376908; PubMed Central PMCID: PMC2698346.

 

  • Jöchl C, Loh E, Ploner A, Haas H, Hüttenhofer A. Development-dependent scavenging of nucleic acids in the filamentous fungus Aspergillus fumigatus. RNA Biol. 2009 Apr-Jun;6(2):179-86. Epub 2009 Apr 28. PubMed PMID: 19246986.

 

2008

  • Wollensak G, Redl B. Gel electrophoretic analysis of corneal collagen after photodynamic cross-linking treatment. Cornea. 2008 Apr;27(3):353-6. doi: 10.1097/ICO.0b013e31815cf66a. PubMed PMID: 18362667.

 

  • Fluckinger M, Merschak P, Hermann M, Haertl√© T, Redl B. Lipocalin-interacting-membrane-receptor (LIMR) mediates cellular internalization of beta-lactoglobulin. Biochim Biophys Acta. 2008 Jan;1778(1):342-7. Epub 2007 Oct 18. PubMed PMID: 17991420.

 

  • Pfister D, De Mulder K, Hartenstein V, Kuales G, Borgonie G, Marx F, Morris J, Ladurner P. Flatworm stem cells and the germ line: developmental and evolutionary implications of macvasa expression in Macrostomum lignano. Dev Biol. 2008 Jul 1;319(1):146-59. doi: 10.1016/j.ydbio.2008.02.045. Epub 2008 Mar 6. PubMed PMID: 18405892.

 

  • Morettini S, Podhraski V, Lusser A. ATP-dependent chromatin remodeling enzymes and their various roles in cell cycle control. Front Biosci. 2008 May 1;13:5522-32. Review. PubMed PMID: 18508602.

 

  • Meraner J, Lechner M, Schwarze F, Gander R, Jesacher F, Loidl P. Cell cycle dependent role of HDAC1 for proliferation control through modulating ribosomal DNA transcription. Cell Biol Int. 2008 Sep;32(9):1073-80. doi: 10.1016/j.cellbi.2008.04.018. Epub 2008 May 2. PubMed PMID: 18550396.

 

  • Brosch G, Loidl P, Graessle S. Histone modifications and chromatin dynamics: a focus on filamentous fungi. FEMS Microbiol Rev. 2008 May;32(3):409-39. doi: 10.1111/j.1574-6976.2007.00100.x. Epub 2008 Jan 23. Review. PubMed PMID: 18221488; PubMed Central PMCID: PMC2442719.

 

  • Mai A, Valente S, Nebbioso A, Simeoni S, Ragno R, Massa S, Brosch G, De Bellis F, Manzo F, Altucci L. New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations. Int J Biochem Cell Biol. 2009 Jan;41(1):235-47. doi: 10.1016/j.biocel.2008.09.002. Epub 2008 Sep 12. PubMed PMID: 18834955.

 

  • Mai A, Cheng D, Bedford MT, Valente S, Nebbioso A, Perrone A, Brosch G, Sbardella G, De Bellis F, Miceli M, Altucci L. epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors. J Med Chem. 2008 Apr 10;51(7):2279-90. doi: 10.1021/jm701595q. Epub 2008 Mar 19. PubMed PMID: 18348515. 104: McDonagh A, Fedorova ND, Crabtree J, Yu Y, Kim S, Chen D, Loss O, Cairns T, Goldman G, Armstrong-James D, Haynes K, Haas H, Schrettl M, May G, Nierman WC, Bignell E. Sub-telomere directed gene expression during initiation of invasive aspergillosis. PLoS Pathog. 2008 Sep 12;4(9):e1000154. doi: 10.1371/journal.ppat.1000154. PubMed PMID: 18787699; PubMed Central PMCID: PMC2526178.

 

  • Schrettl M, Kim HS, Eisendle M, Kragl C, Nierman WC, Heinekamp T, Werner ER, Jacobsen I, Illmer P, Yi H, Brakhage AA, Haas H. SreA-mediated iron regulation in Aspergillus fumigatus. Mol Microbiol. 2008 Oct;70(1):27-43. doi: 1111/j.1365-2958.2008.06376.x. Epub 2008 Aug 21. PubMed PMID: 18721228; PubMed Central PMCID: PMC2610380.

 

  • Haas H, Eisendle M, Turgeon BG. Siderophores in fungal physiology and virulence. Annu Rev Phytopathol. 2008;46:149-87. doi: 10.1146/annurev.phyto.45.062806.094338. Review. PubMed PMID: 18680426.

 

  • Jöchl C, Rederstorff M, Hertel J, Stadler PF, Hofacker IL, Schrettl M, Haas H, Hüttenhofer A. Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis. Nucleic Acids Res. 2008 May;36(8):2677-89. doi: 10.1093/nar/gkn123. Epub 2008 Mar 16. PubMed PMID: 18346967; PubMed Central PMCID: PMC2377427.

 

  • Purschwitz J, Müller S, Kastner C, Schöser M, Haas H, Espeso EA, Atoui A, Calvo AM, Fischer R. Functional and physical interaction of blue- and red-light sensors in Aspergillus nidulans. Curr Biol. 2008 Feb 26;18(4):255-9. doi: 10.1016/j.cub.2008.01.061. PubMed PMID: 18291652.

 

  • Blum G, Perkhofer S, Haas H, Schrettl M, Würzner R, Dierich MP, Lass-Flörl C. Potential basis for amphotericin B resistance in Aspergillus terreus. Antimicrob Agents Chemother. 2008 Apr;52(4):1553-5. doi: 10.1128/AAC.01280-07. Epub 2008 Feb 11. PubMed PMID: 18268082; PubMed Central PMCID: PMC2292529.

 

2007

  • Teufel L, Schuster KC, Merschak P, Bechtold T, Redl B. Development of a fast and reliable method for the assessment of microbial colonization and growth on textiles by DNA quantification. J Mol Microbiol Biotechnol. 2008;14(4):193-200. Epub 2007 Sep 20. PubMed PMID: 17878710.

 

  • Gasymov OK, Abduragimov AR, Merschak P, Redl B, Glasgow BJ. Oligomeric state of lipocalin-1 (LCN1) by multiangle laser light scattering and fluorescence anisotropy decay. Biochim Biophys Acta. 2007 Oct;1774(10):1307-15. Epub 2007 Aug 14. PubMed PMID: 17869594; PubMed Central PMCID: PMC2040513.

 

  • Hagen S, Marx F, Ram AF, Meyer V. The antifungal protein AFP from Aspergillus giganteus inhibits chitin synthesis in sensitive fungi. Appl Environ Microbiol. 2007 Apr;73(7):2128-34. Epub 2007 Feb 2. PubMed PMID: 17277210; PubMed Central PMCID: PMC1855660.

 

  • Konev AY, Tribus M, Park SY, Podhraski V, Lim CY, Emelyanov AV, Vershilova E, Pirrotta V, Kadonaga JT, Lusser A, Fyodorov DV. CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo. Science. 2007 Aug 24;317(5841):1087-90. PubMed PMID: 17717186; PubMed Central PMCID: PMC3014568.

 

  • Shwab EK, Bok JW, Tribus M, Galehr J, Graessle S, Keller NP. Histone deacetylase activity regulates chemical diversity in Aspergillus. Eukaryot Cell. 2007 Sep;6(9):1656-64. Epub 2007 Jul 6. PubMed PMID: 17616629; PubMed Central PMCID: PMC2043372.

 

  • Ragno R, Simeoni S, Rotili D, Caroli A, Botta G, Brosch G, Massa S, Mai A. Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies. Eur J Med Chem. 2008 Mar;43(3):621-32. Epub 2007 May 27. PubMed PMID: 17698257.

 

  • Mai A, Jelicic K, Rotili D, Di Noia A, Alfani E, Valente S, Altucci L, Nebbioso A, Massa S, Galanello R, Brosch G, Migliaccio AR, Migliaccio G. Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia. Mol Pharmacol. 2007 Nov;72(5):1111-23. Epub 2007 Jul 31. PubMed PMID: 17666592.

 

  • Spannhoff A, Machmur R, Heinke R, Trojer P, Bauer I, Brosch G, Schüle R, Hanefeld W, Sippl W, Jung M. A novel arginine methyltransferase inhibitor with cellular activity. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4150-3. Epub 2007 Jun 3. PubMed PMID: 17570663.

 

  • Mai A, Valente S, Rotili D, Massa S, Botta G, Brosch G, Miceli M, Nebbioso A, Altucci L. Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity. Int J Biochem Cell Biol. 2007;39(7-8):1510-22. Epub 2007 Apr 4. PubMed PMID: 17482499.

 

  • Mai A, Valente S, Cheng D, Perrone A, Ragno R, Simeoni S, Sbardella G, Brosch G, Nebbioso A, Conte M, Altucci L, Bedford MT. Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors. ChemMedChem. 2007 Jul;2(7):987-91. PubMed PMID: 17458842.

 

  • Spannhoff A, Heinke R, Bauer I, Trojer P, Metzger E, Gust R, Schüle R, Brosch G, Sippl W, Jung M. Target-based approach to inhibitors of histone arginine methyltransferases. J Med Chem. 2007 May 17;50(10):2319-25. Epub 2007 Apr 14. PubMed PMID: 17432842.

 

  • Ragno R, Simeoni S, Castellano S, Vicidomini C, Mai A, Caroli A, Tramontano A, Bonaccini C, Trojer P, Bauer I, Brosch G, Sbardella G. Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations. J Med Chem. 2007 Mar 22;50(6):1241-53. Epub 2007 Feb 27. PubMed PMID: 17323938.

 

  • Mai A, Rotili D, Massa S, Brosch G, Simonetti G, Passariello C, Palamara AT. Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1221-5. Epub 2006 Dec 12. PubMed PMID: 17196388.

 

  • Schrettl M, Bignell E, Kragl C, Sabiha Y, Loss O, Eisendle M, Wallner A, Arst HN Jr, Haynes K, Haas H. Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection. PLoS Pathog. 2007 Sep 28;3(9):1195-207. PubMed PMID: 17845073; PubMed Central PMCID: PMC1971116.

 

  • Kragl C, Schrettl M, Abt B, Sarg B, Lindner HH, Haas H. EstB-mediated hydrolysis of the siderophore triacetylfusarinine C optimizes iron uptake of Aspergillus fumigatus. Eukaryot Cell. 2007 Aug;6(8):1278-85. Epub 2007 Jun 22. PubMed PMID: 17586718; PubMed Central PMCID: PMC1951140.

 

  • Hortschansky P, Eisendle M, Al-Abdallah Q, Schmidt AD, Bergmann S, Thön M, Kniemeyer O, Abt B, Seeber B, Werner ER, Kato M, Brakhage AA, Haas H. Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron. EMBO J. 2007 Jul 11;26(13):3157-68. Epub 2007 Jun 14. PubMed PMID: 17568774; PubMed Central PMCID: PMC1914100.

 

2006

  • Meraner J, Lechner M, Loidl A, Goralik-Schramel M, Voit R, Grummt I, Loidl P. Acetylation of UBF changes during the cell cycle and regulates the interaction of UBF with RNA polymerase I. Nucleic Acids Res. 2006 Mar 31;34(6):1798-806. Print 2006. PubMed PMID: 16582105; PubMed Central PMCID: PMC1421502.

 

  • Mai A, Massa S, Rotili D, Simeoni S, Ragno R, Botta G, Nebbioso A, Miceli M, Altucci L, Brosch G. Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. J Med Chem. 2006 Oct 5;49(20):6046-56. PubMed PMID: 17004718.

 

  • Mai A, Massa S, Valente S, Simeoni S, Ragno R, Bottoni P, Scatena R, Brosch G. Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition. ChemMedChem. 2006 Feb;1(2):225-37. PubMed PMID: 16892355. Oide S, Moeder W, Krasnoff S, Gibson D, Haas H, Yoshioka K, Turgeon BG. NPS6, encoding a nonribosomal peptide synthetase involved in siderophore-mediated iron metabolism, is a conserved virulence determinant of plant pathogenic ascomycetes. Plant Cell. 2006 Oct;18(10):2836-53. Epub 2006 Oct 20. PubMed PMID: 17056706; PubMed Central PMCID: PMC1626607.

 

  • Eisendle M, Schrettl M, Kragl C, Müller D, Illmer P, Haas H. The intracellular siderophore ferricrocin is involved in iron storage, oxidative-stress resistance, germination, and sexual development in Aspergillus nidulans. Eukaryot Cell. 2006 Oct;5(10):1596-603. PubMed PMID: 17030991; PubMed Central PMCID: PMC1595343.

 

2005

  • Saaren-Sepp√§l√§ H, Jauhiainen M, Tervo TM, Redl B, Kinnunen PK, Holopainen JM. Interaction of purified tear lipocalin with lipid membranes. Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3649-56. PubMed PMID: 16186346.

 

  • Margesin R, Fonteyne PA, Redl B. Low-temperature biodegradation of high amounts of phenol by Rhodococcus spp. and basidiomycetous yeasts. Res Microbiol. 2005 Jan-Feb;156(1):68-75. PubMed PMID: 15636749.

 

  • Breustedt DA, Kornd√∂rfer IP, Redl B, Skerra A. The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands. J Biol Chem. 2005 Jan 7;280(1):484-93. Epub 2004 Oct 15. PubMed PMID: 15489503.

 

  • Leiter E, Szappanos H, Oberparleiter C, Kaiserer L, Csernoch L, Pusztahelyi T, Emri T, Pócsi I, Salvenmoser W, Marx F. Antifungal protein PAF severely affects the integrity of the plasma membrane of Aspergillus nidulans and induces an apoptosis-like phenotype. Antimicrob Agents Chemother. 2005 Jun;49(6):2445-53. PubMed PMID: 15917545; PubMed Central PMCID: PMC1140496.

 

  • Galgóczy L, Papp T, Leiter E, Marx F, Pócsi I, Vágvölgyi C. Sensitivity of different zygomycetes to the Penicillium chrysogenum antifungal protein (PAF). J Basic Microbiol. 2005;45(2):136-41. PubMed PMID: 15812858.

 

  • Szappanos H, Szigeti GP, Pál B, Rusznák Z, Szucs G, Rajnavölgyi E, Balla J, Balla G, Nagy E, Leiter E, Pócsi I, Marx F, Csernoch L. The Penicillium chrysogenum-derived antifungal peptide shows no toxic effects on mammalian cells in the intended therapeutic concentration. Naunyn Schmiedebergs Arch Pharmacol. 2005 Feb;371(2):122-32. Epub 2005 Feb 9. PubMed PMID: 15702351.

 

  • Theis T, Marx F, Salvenmoser W, Stahl U, Meyer V. New insights into the target site and mode of action of the antifungal protein of Aspergillus giganteus. Res Microbiol. 2005 Jan-Feb;156(1):47-56. PubMed PMID: 15636747.

 

  • Marx F, Salvenmoser W, Kaiserer L, Graessle S, Weiler-Görz R, Zadra I, Oberparleiter C. Proper folding of the antifungal protein PAF is required for optimal activity. Res Microbiol. 2005 Jan-Feb;156(1):35-46. PubMed PMID: 15636746.

 

  • Tribus M, Galehr J, Trojer P, Brosch G, Loidl P, Marx F, Haas H, Graessle S. HdaA, a major class 2 histone deacetylase of Aspergillus nidulans, affects growth under conditions of oxidative stress. Eukaryot Cell. 2005 Oct;4(10):1736-45. PubMed PMID: 16215180; PubMed Central PMCID: PMC1265891.

 

  • Mai A, Massa S, Pezzi R, Simeoni S, Rotili D, Nebbioso A, Scognamiglio A, Altucci L, Loidl P, Brosch G. Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides. J Med Chem. 2005 May 5;48(9):3344-53. PubMed PMID: 15857140.

 

  • Rottmann S, Menkel AR, Bouchard C, Mertsching J, Loidl P, Kremmer E, Eilers M, Lüscher-Firzlaff J, Lilischkis R, Lüscher B. Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2. J Biol Chem. 2005 Apr 22;280(16):15489-92. Epub 2005 Feb 18. PubMed PMID: 15722557. 12: Marx F, Salvenmoser W, Kaiserer L, Graessle S, Weiler-Görz R, Zadra I, Oberparleiter C. Proper folding of the antifungal protein PAF is required for optimal activity. Res Microbiol. 2005 Jan-Feb;156(1):35-46. PubMed PMID: 15636746.

 

  • Vietor I, Kurzbauer R, Brosch G, Huber LA. TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent. J Biol Chem. 2005 Dec 2;280(48):39795-801. Epub 2005 Oct PubMed PMID: 16204248. Mai A, Massa S, Rotili D, Pezzi R, Bottoni P, Scatena R, Meraner J, Brosch G. Exploring the connection unit in the HDAC inhibitor pharmacophore model: novel uracil-based hydroxamates. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4656-61. PubMed PMID: 16165353.

 

  • Vance KW, Carreira S, Brosch G, Goding CR. Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas. Cancer Res. 2005 Mar 15;65(6):2260-8. PubMed PMID: 15781639.

 

  • Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, Abe K, Archer DB, Bermejo C, Bennett J, Bowyer P, Chen D, Collins M, Coulsen R, Davies R, Dyer PS, Farman M, Fedorova N, Fedorova N, Feldblyum TV, Fischer R, Fosker N, Fraser A, García JL, García MJ, Goble A, Goldman GH, Gomi K, Griffith-Jones S, Gwilliam R, Haas B, Haas H, Harris D, Horiuchi H, Huang J, Humphray S, Jiménez J, Keller N, Khouri H, Kitamoto K, Kobayashi T, Konzack S, Kulkarni R, Kumagai T, Lafon A, Latgé JP, Li W, Lord A, Lu C, Majoros WH, May GS, Miller BL, Mohamoud Y, Molina M, Monod M, Mouyna I, Mulligan S, Murphy L, O'Neil S, Paulsen I, Peñalva MA, Pertea M, Price C, Pritchard BL, Quail MA, Rabbinowitsch E, Rawlins N, Rajandream MA, Reichard U, Renauld H, Robson GD, Rodriguez de Córdoba S, Rodríguez-Peña JM, Ronning CM, Rutter S, Salzberg SL, Sanchez M, Sánchez-Ferrero JC, Saunders D, Seeger K, Squares R, Squares S, Takeuchi M, Tekaia F, Turner G, Vazquez de Aldana CR, Weidman J, White O, Woodward J, Yu JH, Fraser C, Galagan JE, Asai K, Machida M, Hall N, Barrell B, Denning DW. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature. 2005 Dec 22;438(7071):1151-6. Erratum in: Nature.  2006 Jan 26;439(7075):502. Lafton, Anne [corrected to Lafon, Anne]. PubMed PMID: 

 

  • Tribus M, Galehr J, Trojer P, Brosch G, Loidl P, Marx F, Haas H, Graessle S. HdaA, a major class 2 histone deacetylase of Aspergillus nidulans, affects growth under conditions of oxidative stress. Eukaryot Cell. 2005 Oct;4(10):1736-45. PubMed PMID: 16215180; PubMed Central PMCID: PMC1265891.

 

2004

  • Ladurner P, Pfister D, Seifarth C, Schärer L, Mahlknecht M, Salvenmoser W, Gerth R, Marx F, Rieger R. Production and characterisation of cell- and tissue-specific monoclonal antibodies for the flatworm Macrostomum sp. Histochem Cell Biol. 2005 Jan;123(1):89-104. Epub 2004 Nov 18. PubMed PMID: 15551153.

 

  • Trojer P, Dangl M, Bauer I, Graessle S, Loidl P, Brosch G. Histone methyltransferases in Aspergillus nidulans: evidence for a novel enzyme with a unique substrate specificity. Biochemistry. 2004 Aug 24;43(33):10834-43. PubMed PMID: 15311944.

 

  • Loidl P. A plant dialect of the histone language. Trends Plant Sci. 2004 Feb;9(2):84-90. Review. PubMed PMID: 15102374.

 

  • Hildmann C, Ninkovic M, Dietrich R, Wegener D, Riester D, Zimmermann T, Birch OM, Bernegger C, Loidl P, Schwienhorst A. A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases. J Bacteriol. 2004 Apr;186(8):2328-39. PubMed PMID: 15060035; PubMed Central PMCID: PMC412110.

 

  • Ragno R, Mai A, Massa S, Cerbara I, Valente S, Bottoni P, Scatena R, Jesacher F, Loidl P, Brosch G. 3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies. J Med Chem. 2004 Mar 11;47(6):1351-9. PubMed PMID: 14998325.

 

  • Mai A, Massa S, Cerbara I, Valente S, Ragno R, Bottoni P, Scatena R, Loidl P, Brosch G. 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity. J Med Chem. 2004 Feb 26;47(5):1098-109. PubMed PMID: 14971890.

 

  • Schrettl M, Winkelmann G, Haas H. Ferrichrome in Schizosaccharomyces pombe--an iron transport and iron storage compound. 2004 Dec;17(6):647-54. PubMed PMID: 15689108.

 

  • Schrettl M, Bignell E, Kragl C, Joechl C, Rogers T, Arst HN Jr, Haynes K, Haas H. Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence. J Exp Med. 2004 Nov 1;200(9):1213-9. Epub 2004 Oct 25. PubMed PMID: 15504822; PubMed Central PMCID: PMC2211866.

 

  • Fluckinger M, Haas H, Merschak P, Glasgow BJ, Redl B. Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophores. Antimicrob Agents Chemother. 2004 Sep;48(9):3367-72. PubMed PMID: 15328098; PubMed Central PMCID: PMC514737.

 

  • Eisendle M, Oberegger H, Buttinger R, Illmer P, Haas H. Biosynthesis and uptake of siderophores is controlled by the PacC-mediated ambient-pH Regulatory system in Aspergillus nidulans. Eukaryot Cell. 2004 Apr;3(2):561-3. PubMed PMID: 15075286; PubMed Central PMCID: PMC387658.

 

2003

  • Wojnar P, Lechner M, Redl B. Antisense down-regulation of lipocalin-interacting membrane receptor expression inhibits cellular internalization of lipocalin-1 in human NT2 cells. J Biol Chem. 2003 May 2;278(18):16209-15. Epub 2003 Feb 18. PubMed PMID: 12591932.

 

  • Kaiserer L, Oberparleiter C, Weiler-Görz R, Burgstaller W, Leiter E, Marx F. Characterization of the Penicillium chrysogenum antifungal protein PAF. Arch Microbiol. 2003 Sep;180(3):204-10. Epub 2003 Jul 10. PubMed PMID: 12856109.

 

  • Mai A, Massa S, Pezzi R, Rotili D, Loidl P, Brosch G. Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A. J Med Chem. 2003 Nov 6;46(23):4826-9. PubMed PMID: 14584932.

 

  • Pipal A, Goralik-Schramel M, Lusser A, Lanzanova C, Sarg B, Loidl A, Lindner H, Rossi V, Loidl P. Regulation and processing of maize histone deacetylase Hda1 by limited proteolysis. Plant Cell. 2003 Aug;15(8):1904-17. PubMed PMID: 12897261; PubMed Central PMCID: PMC167178.

 

  • Trojer P, Brandtner EM, Brosch G, Loidl P, Galehr J, Linzmaier R, Haas H, Mair K, Tribus M, Graessle S. Histone deacetylases in fungi: novel members, new facts. Nucleic Acids Res. 2003 Jul 15;31(14):3971-81. PubMed PMID: 12853613; PubMed Central PMCID: PMC167634.

 

  • Mai A, Massa S, Ragno R, Cerbara I, Jesacher F, Loidl P, Brosch G. 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures. J Med Chem. 2003 Feb 13;46(4):512-24. PubMed PMID: 12570373.

 

  • Oberegger H, Eisendle M, Schrettl M, Graessle S, Haas H. 4'-phosphopantetheinyl transferase-encoding npgA is essential for siderophore biosynthesis in Aspergillus nidulans. Curr Genet. 2003 Dec;44(4):211-5. Epub 2003 Sep 24. PubMed PMID: 14508603.

 

  • Oberparleiter C, Kaiserer L, Haas H, Ladurner P, Andratsch M, Marx F. Active internalization of the Penicillium chrysogenum antifungal protein PAF in sensitive aspergilli. Antimicrob Agents Chemother. 2003 Nov;47(11):3598-601. PubMed PMID: 14576124; PubMed Central PMCID: PMC253792.

 

  • Oberegger H, Eisendle M, Schrettl M, Graessle S, Haas H. 4'-phosphopantetheinyl transferase-encoding npgA is essential for siderophore biosynthesis in Aspergillus nidulans. Curr Genet. 2003 Dec;44(4):211-5. Epub 2003 Sep 24. PubMed PMID: 14508603.

 

  • Trojer P, Brandtner EM, Brosch G, Loidl P, Galehr J, Linzmaier R, Haas H, Mair K, Tribus M, Graessle S. Histone deacetylases in fungi: novel members, new facts. Nucleic Acids Res. 2003 Jul 15;31(14):3971-81. PubMed PMID: 12853613; PubMed Central PMCID: PMC167634.

 

  • Eisendle M, Oberegger H, Zadra I, Haas H. The siderophore system is essential for viability of Aspergillus nidulans: functional analysis of two genes encoding l-ornithine N 5-monooxygenase (sidA) and a non-ribosomal peptide synthetase (sidC). Mol Microbiol. 2003 Jul;49(2):359-75. PubMed PMID: 12828635.

 

  • Greene AV, Keller N, Haas H, Bell-Pedersen D. A circadian oscillator in Aspergillus spp. regulates daily development and gene expression. Eukaryot Cell. 2003 Apr;2(2):231-7. PubMed PMID: 12684372; PubMed Central PMCID: PMC154850.

 

  • Haas H, Schoeser M, Lesuisse E, Ernst JF, Parson W, Abt B, Winkelmann G, Oberegger H. Characterization of the Aspergillus nidulans transporters for the siderophores enterobactin and triacetylfusarinine C. Biochem J. 2003 Apr 15;371(Pt 2):505-13. PubMed PMID: 12487628; PubMed Central PMCID: PMC1223275.

 

2002

  • Wojnar P, Dirnhofer S, Ladurner P, Berger P, Redl B. Human lipocalin-1, a physiological scavenger of lipophilic compounds, is produced by corticotrophs of the pituitary gland. J Histochem Cytochem. 2002 Mar;50(3):433-5. PubMed PMID: Saurwein-Teissl M, Lung TL, Marx F, Gschösser C, Asch E, Blasko I, Parson W, Böck G, Schönitzer D, Trannoy E, Grubeck-Loebenstein B. Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J Immunol. 2002 Jun 1;168(11):5893-9. PubMed PMID: 12023394.

 

  • Brandtner EM, Lechner T, Loidl P, Lusser A. Molecular identification of PpHDAC1, the first histone deacetylase fron the slime mold Physarum polycephalum. Cell Biol Int. 2002;26(9):783-9. PubMed PMID: 12377210.

 

  • Wittich S, Scherf H, Xie C, Brosch G, Loidl P, Gerhäuser C, Jung M. Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. J Med Chem. 2002 Jul 18;45(15):3296-309. PubMed PMID: 12109913.

 

  • Mai A, Massa S, Ragno R, Esposito M, Sbardella G, Nocca G, Scatena R, Jesacher F, Loidl P, Brosch G. Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. J Med Chem. 2002 Apr 25;45(9):1778-84. PubMed PMID: 11960489.

 

  • Baidyaroy D, Brosch G, Graessle S, Trojer P, Walton JD. Characterization of inhibitor-resistant histone deacetylase activity in plant-pathogenic fungi. Eukaryot Cell. 2002 Aug;1(4):538-47. PubMed PMID: 12456002; PubMed Central PMCID: PMC118000.

 

  • Vietor I, Vadivelu SK, Wick N, Hoffman R, Cotten M, Seiser C, Fialka I, Wunderlich W, Haase A, Korinkova G, Brosch G, Huber LA. TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells. EMBO J. 2002 Sep 2;21(17):4621-31. PubMed PMID: 12198164; PubMed Central PMCID: PMC125408.

 

  • Chiocca S, Kurtev V, Colombo R, Boggio R, Sciurpi MT, Brosch G, Seiser C, Draetta GF, Cotten M. Histone deacetylase 1 inactivation by an adenovirus early gene product. Curr Biol. 2002 Apr 2;12(7):594-8. PubMed PMID: 11937030.

 

  • Oberegger H, Schoeser M, Zadra I, Schrettl M, Parson W, Haas H. Regulation of freA, acoA, lysF, and cycA expression by iron availability in Aspergillus nidulans. Appl Environ Microbiol. 2002 Nov;68(11):5769-72. PubMed PMID: 12406779; PubMed Central PMCID: PMC129941.

 

2001

  • Baidyaroy, D.; Brosch, G.; Ahn, JH.; Graessle, S.; Wegener, S.; Tonukari, NJ.; Caballero, O.; Loidl, P.; Walton, JD.: A Gene-Related To Yeast Hos2 Histone Deacetylase Affects Extracellular Depolymerase Expression And Virulence In A Plant-Pathogenic Fungus.  PLANT CELL. 2001; 13; 1609-1624.  PubMed: 11449054

 

  • Brosch, G.; Dangl, M.; Graessle, S.; Loidl, A.; Trojer, P.; Brandtner, EM.; Mair, K.; Walton, JD.; Baidyaroy, D.; Loidl, P.: An Inhibitor-Resistant Histone Deacetylase In The Plant-Pathogenic Fungus Cochliobolus-Carbonum.  2001; 40; 12855-12863.  PubMed: 11669622

 

  • Conlon, H.; Zadra, I.; Haas, H.; Arst, HN.; Jones, MG.; Caddick, MX.: The Aspergillus-Nidulans Gata Transcription Factor Gene Areb Encodes At Least 3 Proteins And Features 3 Classes Of Mutation.  MOLECULAR MICROBIOLOGY. 2001; 40; 361-375.  PubMed: 11309119

 

  • Dangl, M.; Brosch, G.; Haas, H.; Loidl, P.; Lusser, A.: Comparative-Analysis Of Hd2 Type Histone Deacetylases In Higher-Plants.  2001; 213; 280-285.  PubMed: 11469594

 

  • Graessle, S.; Loidl, P.; Brosch, G.: Histone Acetylation - Plants And Fungi As Model Systems For The Investigation Of Histone Deacetylases.  CELLULAR AND MOLECULAR LIFE SCIENCES. 2001; 58; 704-720.  PubMed: 11437232

 

  • Lechner, M.; Wojnar, P.; Redl, B.: Human Tear Lipocalin Acts As An Oxidative-Stress-Induced Scavenger Of Potentially Harmful Lipid-Peroxidation Products In A Cell-Culture System.  BIOCHEMICAL JOURNAL. 2001; 356; 129-135.  PubMed: 11336644

 

  • Loidl, P.: Introduction - Assembly, Remodeling And Modification Of Chromatin.  CELLULAR AND MOLECULAR LIFE SCIENCES. 2001; 58; 663-664.  PubMed: 11437227

 

  • Lusser, A.; Kolle, D.; Loidl, P.: Histone Acetylation - Lessons From The Plant Kingdom.  TRENDS IN PLANT SCIENCE. 2001; 6; 59-65.  PubMed: 11173289

 

  • Marx, F.; Gritsun, TS.; Grubeck-Loebenstein, B.; Gould, EA.: Diagnostic Immunoassays For Tick-Borne Encephalitis-Virus Based On Recombinant Baculovirus Protein Expression.  JOURNAL OF VIROLOGICAL METHODS. 2001; 91; 75-84.  PubMed: 11164488

 

  •  Massa, S.; Mai, A.; Sbardella, G.; Esposito, M.; Ragno, R.; Loidl, P.; Brosch, G.: 3-(4-Aroyl-1h-Pyrrol-2-Yl)-N-Hydroxy-2-Propenamides, A New Class Of Synthetic Histone Deacetylase Inhibitors.  JOURNAL OF MEDICINAL CHEMISTRY. 2001; 44; 2069-2072.  PubMed: 11405644

 

  • Oberegger, H.; Schoeser, M.; Zadra, I.; Abt, B.; Haas, H.: Srea Is Involved In Regulation Of Siderophore Biosynthesis, Utilization And Uptake In Aspergillus-Nidulans.  MOLECULAR MICROBIOLOGY. 2001; 41; 1077-1089.  PubMed: 11555288

 

  • Taplick, J.; Kurtev, V.; Kroboth, K.; Posch, M.; Lechner, T.; Seiser, C.: Homooligomerization And Nuclear-Localization Of Mouse Histone Deacetylase-1.  JOURNAL OF MOLECULAR BIOLOGY. 2001; 308; 27-38.  PubMed: 11302704

 

  • Wagner, M.; Brosch, G.; Zwerschke, W.; Seto, E.; Loidl, P.; Jansen-Durr, P.: Histone Deacetylases In Replicative Senescence - Evidence For A Senescence-Specific Form Of Hdac-2.  FEBS LETTERS. 2001; 499; 101-106.  PubMed: 11418121

 

  • Wojnar, P.; Lechnar, M.; Merschak, P.; Redl, B.: Molecular-Cloning Of A Novel Lipocalin-1 Interacting Human Cell-Membrane Receptor Using Phage Display.  JOURNAL OF BIOLOGICAL CHEMISTRY. 2001; 276; 20206-20212.  PubMed: 11036079

 

  •  Wojnar, P.; van't Hof, W.; Merschak, P.; Lechner, M.; Redl, B.: The N-Terminal Part Of Recombinant Human Tear Lipocalin/Von Ebners Gland Protein Confers Cysteine Proteinase Inhibition Depending On The Presence Of The Entire Cystatin-Like Sequence Motifs.  BIOLOGICAL CHEMISTRY. 2001; 382; 1515-1520.  PubMed: 11727836

 

 2000

  • Berger, MM.; Kopp, N.; Vital, C.; Redl, B.; Aymard, M.; Lina, B.: Detection And Cellular-Localization Of Enterovirus Rna Sequences In Spinal-Cord Of Patients With Als.  2000; 54; 20-25.  PubMed: 10636120

 

  • Feng, B.; Haas, H.; Marzluf, GA.: Asd4, A New Cata Factor Of Neurospora-Crassa, Displays Sequence-Specific Dna-Binding And Functions In Ascus And Ascospore Development.  2000; 39; 11065-11073.  PubMed: 10998244

 

  • Graessle, S.; Dangl, M.; Haas, H.; Mair, K.; Trojer, P.; Brandtner, EM.; Walton, JD.; Loidl, P.; Brosch, G.: Characterization Of 2 Putative Histone Deacetylase Genes From Aspergillus-Nidulans. 
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. 2000; 1492; 120-126. 
    PubMed: 11004483

 

  • Hoffmann, K.; Brosch, G.; Loidl, P.; Jung, M.: First Nonradioactive Assay For In-Vitro Screening Of Histone Deacetylase Inhibitors.  2000; 55; 601-606.  PubMed: 10989838

 

  • Lechner, T.; Carrozza, MJ.; Yu, YX.; Grant, PA.; Eberharter, A.; Vannier, D.; Brosch, G.; Stillman, DJ.; Shore, D.; Workman, JL.: Sds3 (Suppressor Of Defective Silencing-3) Is An Integral Component Of The Yeast Sin3-Center-Dot-Rpd3 Histone Deacetylase Complex And Is Required For Histone Deacetylase Activity.  JOURNAL OF BIOLOGICAL CHEMISTRY. 2000; 275; 40961-40966.  PubMed: 11024051

 

  • Lechner, T.; Lusser, A.; Pipal, A.; Brosch, G.; Loidl, A.; Goralik-Schramel, M.; Sendra, R.; Wegener, S.; Walton, JD.; Loidl, P.: Rpd3-Type Histone Deacetylases In Maize Embryos.  2000; 39; 1683-1692.  PubMed: 10677216

 

  • Oberegger, H.; Zadra, I.; Schoeser, M.; Haas, H.: Iron Starvation Leads To Increased Expression Of Cu/Zn-Superoxide Dismutase In Aspergillus.  FEBS LETTERS. 2000; 485; 113-116.  PubMed: 11094151

 

  • Redl, B.: Human Tear Lipocalin.  BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY. 2000; 1482; 241-248.  PubMed: 11058765

 

  •  Zadra, I.; Abt, B.; Parson, W.; Haas, H.: Xylp Promoter-Based Expression System And Its Use For Antisense Down-Regulation Of The Penicillium-Chrysogenum Nitrogen Regulator Nre.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2000; 66; 4810-+.  PubMed: 11055928

 

1999

  • Angermayr, K.; Parson, W.; Stoffler, G.; Haas, H.: Expression Of Atrc - Encoding A Novel Member Of The Atp Binding Cassette Transporter Family In Aspergillus-Nidulans - Is Sensitive To Cycloheximide.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 1999; 1453; 304-310.  PubMed: 10036328

 

  • Cepica, S.; Schroffel, J.; Redl, B.; Rohrer, GA.: Linkage Mapping Of 2 Taqi Pcr-Rflps Within Intron-6 Of The Porcine Gene (Lcn1) Encoding Tear Llipocalin/Von Ebners Gland Protein.  ANIMAL GENETICS. 1999; 30; 467-468.  PubMed: 10612245

 

  • Cepica, S.; Yerle, M.; Stratil, A.; Schroffel, J.; Redl, B.: Regional Localization Of Porcine Myod1, Myf5, Lep, Ucp3 And Lcn1 Genes.  ANIMAL GENETICS. 1999; 30; 476-478.  PubMed: 10612255

 

  • Doetzlhofer, A.; Rotheneder, H.; Lagger, G.; Koranda, M.; Kurtev, V.; Brosch, G.; Wintersberger, E.; Seiser, C.: Histone Deacetylase-1 Can Repress Transcription By Binding To Sp1.  MOLECULAR AND CELLULAR BIOLOGY. 1999; 19; 5504-5511.  PubMed: 10409740

 

  • Graessle, S.; Grabher, G.; Gapp, G.; Preuss, E.; Datz, C.; Sandhofer, F.; Stoffler, G.: Immune-Response To Natural And Recombinant Antigens Of Helicobacter-Pylori In Patients With Dyspeptic Complaints.  EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 1999; 18; 636-642.  PubMed: 10534185

 

  • Haas, H.; Zadra, I.; Stoffler, G.; Angermayr, K.: The Aspergillus-Nidulans Gata Factor Srea Is Involved In Regulation Of Siderophore Biosynthesis And Control Of Iron Uptake.  JOURNAL OF BIOLOGICAL CHEMISTRY. 1999; 274; 4613-4619.  PubMed: 9988696

 

  • Hoffmann, K.; Brosch, G.; Loidl, P.; Jung, M.: A Nonisotopic Assay For Histone Deacetylase Activity.  NUCLEIC ACIDS RESEARCH. 1999; 27; 2057-2058.  PubMed: 10198441

 

  • Jung, M.; Brosch, G.; Kolle, D.; Scherf, H.; Gerhauser, C.; Loidl, P.: Amide Analogs Of Trichostatin-A As Inhibitors Of Histone Deacetylase And Inducers Of Terminal Cell-Differentiation.  JOURNAL OF MEDICINAL CHEMISTRY. 1999; 42; 4669-4679.  PubMed: 10579829

 

  • Jungblut, PR.; Grabher, G.; Stoffler, G.: Comprehensive Detection Of Immunorelevant Borrelia-Garinii Antigens By 2-Dimensional Electrophoresis.  1999; 20; 3611-3622.  PubMed: 10612288

 

  • Jungblut, PR.; Zimny-Arndt, U.; Zeindl-Eberhart, E.; Stulik, J.; Koupilova, K.; Pleissner, KP.; Otto, A.; Muller, EC.; Sokolowska-Kohler, W.; Grabher, G.; Stoffler, G.: Proteomics In Human-Disease - Cancer, Heart And Infectious-Diseases. 
    1999; 20; 2100-2110. 
    PubMed: 10451122

 

  • Kolle, D.; Brosch, G.; Lechner, T.; Pipal, A.; Helliger, W.; Taplick, J.; Loidl, P.: Different Types Of Maize Histone Deacetylases Are Distinguished By A Highly Complex Substrate And Site-Specificity.  1999; 38; 6769-6773. 
    PubMed: 10346897

 

  • Lusser, A.; Eberharter, A.; Loidl, A.; Goralik-Schramel, M.; Horngacher, M.; Haas, H.; Loidl, P.: Analysis Of The Histone Acetyltransferase-B Complex Of Maize Embryos.  NUCLEIC ACIDS RESEARCH. 1999; 27; 4427-4435.  PubMed: 10536152

 

  • Neuner-Plattner, I.; Grabher, T.; Hall, IR.; Stoffler, G.; Griffin, F.; Haselwandter, K.: A Comparison Of Immunological Assays For The Identification Of Tuber Spp. And Other Edible Ectomycorrhizal Fungi.  MYCOLOGICAL RESEARCH. 1999; 103; 403-412. 

 

  • Redl, B.; Merschak, P.; Abt, B.; Wojnar, P.: Phage Display Reveals A Novel Interaction Of Human Tear Lipocalin And Thioredoxin Which Is Relevant For Ligand-Binding.  FEBS LETTERS. 1999; 460; 182-186.  PubMed: 10571084

 

  •  Trojer, P.; Wojnar, P.; Merschak, P.; Redl, B.: Complement Component C8-Gamma Is Expressed In Human Fetal And Adult Kidney Independent Of C8-Alpha.  FEBS LETTERS. 1999; 446; 243-246.  PubMed: 10100850

 

1998

  • Bauer, A.; Mikulits, W.; Lagger, G.; Stengl, G.; Brosch, G.; Beug, H.: The Thyroid-Hormone Receptor Functions As A Ligand-Operated Developmental Switch Between Proliferation And Differentiation Of Erythroid Progenitors.  EMBO JOURNAL. 1998; 17; 4291-4303.  PubMed: 9687498

 

  • Kolle, D.; Brosch, G.; Lechner, T.; Lusser, A.; Loidl, P.: Biochemical Methods For Analysis Of Histone Deacetylases. 
    METHODS-A COMPANION TO METHODS IN ENZYMOLOGY. 1998; 15; 323-331.  PubMed: 9740720

 

  • Kolle, D.; Sarg, B.; Lindner, H.; Loidl, P.: Substrate And Sequential Site-Specificity Of Cytoplasmic Histone Acetyltransferases Of Maize And Rat-Liver.  FEBS LETTERS. 1998; 421; 109-114.  PubMed: 9468289

 

  • Redl, B.; Wojnar, P.; Ellemunter, H.; Feichtinger, H.: Identification Of A Lipocalin In Mucosal Glands Of The Human Tracheobronchial Tree And Its Enhanced Secretion In Cystic-Fibrosis.  LABORATORY INVESTIGATION. 1998; 78; 1121-1129. 
    PubMed: 9759656

 

  • Zhou, LW.; Haas, H.; Marzluf, GA.: Isolation And Characterization Of A New Gene, Sre, Which Encodes A Gata-Type Regulatory Protein That Controls Iron Transport In Neurospora-Crassa.  MOLECULAR AND GENERAL GENETICS. 1998; 259; 532-540.  PubMed: 9790585

 

1997

  • Berger, MM.; See, DM.; Redl, B.; Aymard, M.; Bruno, L.: Direct In-Situ Reverse-Transcriptase Polymerase Chain-Reaction For The Detection Of Enterovirus Genome In Liver-Tissues.  JOURNAL OF VIROLOGICAL METHODS. 1997; 65; 55-66. 
    PubMed: 9128862

 

  • Berger, MM.; See, DM.; Redl, B.; Aymard, M.; Lina, B.: Comparison Of Procedures For The Detection Of Enteroviruses In Murine Heart Samples By In-Situ Polymerase-Chain-Reaction.  RESEARCH IN VIROLOGY. 1997; 148; 409-416. 
    PubMed: 9498012

 

  • Graessle, S.; Haas, H.; Friedlin, E.; Kurnsteiner, H.; Stoffler, G.; Redl, B.: Regulated System For Heterologous Gene-Expression In Penicillium-Chrysogenum.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 1997; 63; 753-756.  PubMed: 9023952

 

  • Haas, H.; Angermayr, K.; Stoffler, G.: Molecular Analysis Of A Penicillium-Chrysogenum Gata Factor Encoding Gene (Srep) Exhibiting Significant Homology To The Ustilago-Maydis Urbs1 Gene.  1997; 184; 33-37.  PubMed: 9016950

 

  • Haas, H.; Angermayr, K.; Zadra, I.; Stoffler, G.: Overexpression Of Nreb, A New Gata Factor-Encoding Gene Of Penicillium-Chrysogenum, Leads To Repression Of The Nitrate Assimilatory Gene-Cluster.  JOURNAL OF BIOLOGICAL CHEMISTRY. 1997; 272; 22576-22582.  PubMed: 9278412

 

  • Holzfeind, P.; Merschak, P.; Wojnar, P.; Redl, B.: Structure And Organization Of The Porcine Lcn1 Gene Encoding Tear Lipocalin Von-Ebner Gland Protein.  1997; 202; 61-67.  PubMed: 9427546

 

  • Jung, M.; Hoffmann, K.; Brosch, G.; Loidl, P.: Analogs Of Trichostatin-A And Trapoxin-B As Histone Deacetylase Inhibitors. 
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 1997; 7; 1655-1658. 

 

  • Lusser, A.; Brosch, G.; Loidl, A.; Haas, H.; Loidl, P.: Identification Of Maize Histone Deacetylase Hd2 As An Acidic Nucleolar Phosphoprotein.  1997; 277; 88-91.  PubMed: 9204905

 

  • Lusser, A.; Brosch, G.; LopezRodas, G.; Loidl, P.: Histone Acetyltransferases During The Cell-Cycle And Differentiation Of Physarum-Polycephalum.  EUROPEAN JOURNAL OF CELL BIOLOGY. 1997; 74; 102-110.  PubMed: 9309396

 

  • Sommer, A.; Hilfenhaus, S.; Menkel, A.; Kremmer, E.; Seiser, C.; Loidl, P.; Luscher, B.: Cell-Growth Inhibition By The Mad/Max Complex Through Recruitment Of Histone Deacetylase Activity.  CURRENT BIOLOGY. 1997; 7; 357-365. 
    PubMed: 9197243

 

Institut für Molekularbiologie