Innsbruck Medical University, Biocenter, Institute of Medical Biochemistry, Innrain 80-82, A-6020 Innsbruck

e-mail: johann.hofmann@i-med.ac.at

Phone +43-(0)512-9003-70130 Fax +43-(0)512-9003-73130

Research Areas

Investigations into the function of unknown genes or ESTs regulated by PKCepsilon.
Development of antagonists of PKCepsilon by interference between PKCepsilon and RACK2
Investigations into the mechanism of action of novel bicyclic hydrazones with antitumor activity.

Previously completed Ph. D. or Master Theseses

Eva Margreiter: Thiosemicarbazone-Derivatives as Potential Antitumor Drugs, 2004
Andrea Nessler: The Influence of PKCe on Gene Expression, 2004
Astrid Wolf: Investigations into New Multidrug Resistance Reversing Compounds, 2005
Dorota Garczarczyk: Characterization of C6orf69, a Gene Modulated by Protein Kinase C epsilon, 2005
Florian Rechfeld: Investigations into PKCe-RACK2 interactions, 2008
Simone Stenico: Cloning and purification of RhoBTB3 and C6orf69, 2010
Doris Hinger: Investigations into PKCe-modulated genes, 2010

Biocenter, Area Biochemistry and Chemistry